ArticleThe Journal of veterinary medical science2018
Structural differences in the brain between wild and laboratory rats (Rattus norvegicus): Potential contribution to wariness.
Article in The Journal of veterinary medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Making a case for the free exploratory paradigm: animal welfare-friendly assays that enhance heterozygosity and ecological validity.Frontiers in behavioral neuroscience · 2023Article
- Neurobiological effects of a probiotic-supplemented diet in chronically stressed male Long-Evans rats: Evidence of enhanced resilience.IBRO neuroscience reports · 2021Article
- Existence of wild brown rats (Rattus norvegicus) that are indifferent to novel objects.The Journal of veterinary medical science · 2021Article
- Novel objects elicit greater activation in the basolateral complex of the amygdala of wild rats compared with laboratory rats.The Journal of veterinary medical science · 2019Article
- Communication between the gut microbiota and peripheral nervous system in health and chronic disease.Gut microbesReview
- Beyond the Lab: Cognitive Neuroscience in Real-World Contexts.Wiley interdisciplinary reviews. Cognitive scienceReview
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Authors and funding
7 authors.
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Abstract
Wild animals typically exhibit defensive behaviors in response to a wider range and/or a weaker intensity of stimuli compared with domestic animals. However, little is known about the neural mechanisms underlying "wariness" in wild animals. Wild rats are one of the most accessible wild animals for experimental research. Laboratory rats are a domesticated form of wild rat, belonging to the same species, and are therefore considered suitable control animals for wild rats. Based on these factors, we analyzed structural differences in the brain between wild and laboratory rats to elucidate the neural mechanisms underlying wariness. We examined wild rats trapped in Tokyo, and weight-matched laboratory rats. We then prepared brain sections and compared the basolateral complex of the amygdala (BLA), the bed nucleus of the stria terminalis (BNST), the main olfactory bulb and the accessory olfactory bulb. The results revealed that wild rats exhibited larger BLA, BNST and caudal part of the accessory olfactory bulb compared with laboratory rats. These results suggest that the BLA, BNST, and vomeronasal system potentially contribute to wariness in wild rats.
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