Evidence map›Paper›PMID 29760213›Full record

ArticleInfection and immunity2018

Changes in IgA Protease Expression Are Conferred by Changes in Genomes during Persistent Infection by Nontypeable Haemophilus influenzae in Chronic Obstructive Pulmonary Disease.

Mary C Gallo, Charmaine Kirkham, Samantha Eng, Remon S Bebawee, Yong Kong, Melinda M Pettigrew, Hervé Tettelin, Timothy F Murphy

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Haemophilus influenzae one day in Denmark: prevalence, circulating clones, and dismal resistance to aminopenicillins.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  6. Article
  7. Review
  8. Learning from -omics strategies applied to uncoverComputational and structural biotechnology journal · 2021
    Review
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mary C GalloDepartment of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA.
Charmaine KirkhamClinical and Translational Research Center, University at Buffalo, Buffalo, New York, USA.
Samantha EngClinical and Translational Research Center, University at Buffalo, Buffalo, New York, USA.
Remon S BebaweeClinical and Translational Research Center, University at Buffalo, Buffalo, New York, USA.
Yong KongDepartment of Biostatistics, Yale School of Public Health, Yale University, New Haven, Connecticut, USA.
Melinda M PettigrewDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, Connecticut, USA.
Hervé TettelinInstitute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Timothy F MurphyDepartment of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA murphyt@buffalo.edu.
University at Buffalo, State University of New York · USYale University · USUniversity of Maryland, Baltimore · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Persistent H. influenzae in COPD - virulence, vaccines and antibiotic resistanceR01AI019641 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 1985 to 2023
$7.9M
Training the Next Generation of Physician ScientistsT35AI089693 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Mark Daniel Hicar · 2011 to 2026
$689k
Training - Infectious Disease, Microbiology &ImmunologyT35AI049838 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2001 to 2005
$144k
NCATS NIH HHS UL1 TR001412NIAID NIH HHS R01 AI019641NIAID NIH HHS T35 AI049838NIAID NIH HHS T35 AI089693
6 · The paper itself

Abstract

Nontypeable

Indexed as

Gene ExpressionMutationHaemophilus InfectionsHaemophilus influenzaeHumansLongitudinal StudiesNew YorkProspective StudiesPulmonary Disease, Chronic ObstructiveSerine EndopeptidasesIgA-specific serine endopeptidaseSerine Endopeptidaseschronic obstructive pulmonary diseaseIgA proteasenontypeable Haemophilus influenzaerespiratory tract infections

Identifiers

PMID29760213
PMCPMC6056860
OpenAlexW2801535103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.