Evidence map›Paper›PMID 29760180›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

The Affective and Neural Correlates of Heroin versus Cocaine Use in Addiction Are Influenced by Environmental Setting But in Opposite Directions.

Silvana De Pirro, Gaspare Galati, Luigi Pizzamiglio, Aldo Badiani

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Context features influence alcohol reward and motivation.Alcohol, clinical & experimental research · 2026
    Article
  3. Article
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  5. Article
  6. Article
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  8. Observational
  9. Article
  10. Review
  11. Article
  12. Article
  13. The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  14. Article
  15. The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  16. Review
  17. Article
  18. The role of social isolation in opioid addiction.Social cognitive and affective neuroscience · 2021
    Article
  19. Review
  20. Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure in male mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Silvana De PirroSussex Addiction Research and Intervention Centre (SARIC), School of Psychology, University of Sussex, Brighton, BN1 9QH, United Kingdom, aldo.badiani@sussex.ac.uk S.DePirro@sussex.ac.uk.ORCID 0000-0003-3320-3800
Gaspare GalatiDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy, and.ORCID 0000-0002-0640-4247
Luigi PizzamiglioDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy, and.
Aldo BadianiSussex Addiction Research and Intervention Centre (SARIC), School of Psychology, University of Sussex, Brighton, BN1 9QH, United Kingdom, aldo.badiani@sussex.ac.uk S.DePirro@sussex.ac.uk.ORCID 0000-0001-6885-369X
Fondazione Santa Lucia · ITUniversity of Sussex · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have shown that individuals with heroin and cocaine addiction prefer to use these drugs in distinct settings: mostly at home in the case of heroin and mostly outside the home in the case of cocaine. Here we investigated whether the context would modulate the affective and neural responses to these drugs in a similar way. First, we used a novel emotional task to assess the affective state produced by heroin or cocaine in different settings, based on the recollections of male and female drug users. Then we used fMRI to monitor neural activity during drug imagery (re-creating the setting of drug use) in male drug users. Consistent with our working hypothesis, the majority of participants reported a shift in the affective valence of heroin from mostly pleasant at home to mostly unpleasant outside the home (

Indexed as

EnvironmentAdultAffectBrain MappingCaudate NucleusCerebellumCocaine-Related DisordersCorpus StriatumHeroin DependenceHumansImaginationMagnetic Resonance ImagingMaleMiddle AgedNerve NetNeuronsaddictioncontextemotionfMRIopiatespsychostimulants

Identifiers

PMID29760180
PMCPMC6705939
OpenAlexW2803693945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.