ArticleBlood2018
CTCF boundary remodels chromatin domain and drives aberrant
Open access · bronzeAbstract read
In one paragraph
Article in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 89 citations in OpenAlex.
- Alterations in 3D-DNA architecture drive unique leukemic profiles in IDH1- and DNMT3A-mutant acute myeloid leukemia.Leukemia · 2026Article
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- ChromNet: A Multi-Task Learning Framework for Cross-Cell Type Prediction of 3D Chromatin Interactions Using Epigenetic Signals.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- An upstream secondary DNA motif within the IL3 insulator CTCF binding site is required for enhancer-blocking insulator activity.PloS one · 2026Article
- The METTL3-YTHDC1 axis mediates architectural RNA mMolecular cancer · 2025Article
- Dysregulation of HOXA genes in acute myeloid leukemia and targeted therapy.NPJ precision oncology · 2025Review
- CTCF Is Essential for the Development and Maintenance of CALM-AF10-Induced Leukemia.Cancer science · 2025Article
- Review
- Coupling CRISPR scanning with targeted chromatin accessibility profiling using a double-stranded DNA deaminase.Nature methods · 2025Article
- Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells.bioRxiv : the preprint server for biology · 2025Article
- HoxBlinc lncRNA reprograms CTCF-independent TADs to drive leukemic transcription and HSC dysregulation in NUP98-rearranged leukemia.The Journal of clinical investigation · 2025Article
- Long Non-Coding RNA HCP5 Affects Ferroptosis in Lung Adenocarcinoma through miR-17-5p/HOXA7 Axis.Current cancer drug targets · 2025Article
- Comprehensive analytical approach identifies a subtype of CTCF+ tumor-associated neutrophils associated with CRC development and as a biomarker for immunotherapy.International journal of biological sciences · 2025Article
- TAD-dependent sub-TAD is required for enhancer-promoter interaction enabling the β-globin transcription.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Super-enhancer omics in stem cell.Molecular cancer · 2024Review
- Regulation of HOX gene expression in AML.Blood cancer journal · 2024Review
- Article
- Applying CRISPR-Cas9 screens to dissect hematological malignancies.Blood advances · 2023Review
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 7 institutions in 3 countries.
Huacheng LuoDepartment of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL.
Fei WangDepartment of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL.
Jie ZhaDepartment of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL.
Haoli LiDepartment of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL.
Bowen YanDepartment of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL.
Qinghua DuDepartment of Biochemistry and Molecular Biology, University of Miami Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.
Fengchun YangDepartment of Biochemistry and Molecular Biology, University of Miami Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.
Amin SobhDepartment of Physiological Sciences, University of Florida, Gainesville, FL.
Christopher VulpeDepartment of Physiological Sciences, University of Florida, Gainesville, FL.
Leylah DrusboskyDivision of Hematology/Oncology, Department of Medicine, University of Florida College of Medicine, Gainesville, FL.
Christopher CogleDivision of Hematology/Oncology, Department of Medicine, University of Florida College of Medicine, Gainesville, FL.
Iouri ChepelevCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Bing XuDepartment of Hematology, The First Affiliate Hospital of Xiamen University, Xiamen, China.
Stephen D NimerDepartment of Biochemistry and Molecular Biology, University of Miami Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.
Jonathan LichtDivision of Hematology/Oncology, Department of Medicine, University of Florida College of Medicine, Gainesville, FL.
Yi QiuDepartment of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL.
Baoan ChenDepartment of Hematology and Oncology, The Affiliated Zhongda Hospital, Southeast University Medical School, Nanjing, China.
Mingjiang XuDepartment of Biochemistry and Molecular Biology, University of Miami Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.
Suming HuangDepartment of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL.ORCID 0000-0002-4788-2085
University of Florida · USUniversity of Miami · USUniversity of Florida Health · USCincinnati Children's Hospital Medical Center · USFirst Affiliated Hospital of Xiamen University · CNMacau University of Science and Technology · MOZhongda Hospital Southeast University · CN
Funding
Tumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Daniel Bilbao · 2019 to 2026
$24.1MTargeting p300 and lysine acetylation in AMLR01CA166835 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Stephen D. Nimer · 2012 to 2026
$4.6MRole of Asxl1 in normal hematopoiesis and pathogenesis of myeloid malignanciesR01CA172408 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI XU, MINGJIANG, YANG, FENG-CHUN · 2014 to 2024
$3.4MRole of TET2 in normal hematopoiesis and pathogenesis of myeloid malignanciesR01HL112294 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI XU, MINGJIANG · 2012 to 2016
$1.9MRegulation of TAL1/SCL in T-Cell LeukemiaR01CA204044 · NCI · UNIVERSITY OF FLORIDA · PI HUANG, SUMING · 2017 to 2021
$1.6MThe Role of Long Noncoding RNA in HematopoiesisR01DK110108 · NIDDK · UNIVERSITY OF FLORIDA · PI HUANG, SUMING · 2016 to 2019
$1.3MNCI NIH HHS P30 CA240139NCI NIH HHS R01 CA166835NCI NIH HHS R01 CA172408NCI NIH HHS R01 CA204044NHLBI NIH HHS R01 HL112294NIDDK NIH HHS R01 DK110108
Abstract
PubMed holds no abstract for this paper.
Indexed as
Chromatin Assembly and DisassemblyGene Expression Regulation, LeukemicTranscription, GeneticAnimalsCCCTC-Binding FactorCell Line, TumorCRISPR-Cas SystemsHomeodomain ProteinsHumansLeukemia, Myeloid, AcuteMiceMice, Inbred NODNeoplasm ProteinsCCCTC-Binding FactorCTCF protein, humanHomeodomain ProteinsNeoplasm Proteins
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.