Evidence map›Paper›PMID 29760133›Full record

ArticleAntimicrobial agents and chemotherapy2018

Pharmacokinetics and Safety Profile of Artesunate-Amodiaquine Coadministered with Antiretroviral Therapy in Malaria-Uninfected HIV-Positive Malawian Adults.

Clifford G Banda, Fraction Dzinjalamala, Mavuto Mukaka, Jane Mallewa, Victor Maiden, Dianne J Terlouw, David G Lalloo, Saye H Khoo, Victor Mwapasa

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Clifford G BandaMalawi College of Medicine, Blantyre, Malawi cgbanda@mlw.mw vmwapasa@medcol.mw.ORCID 0000-0002-0757-5259
Fraction DzinjalamalaMalawi College of Medicine, Blantyre, Malawi.
Mavuto MukakaMalawi College of Medicine, Blantyre, Malawi.
Jane MallewaMalawi College of Medicine, Blantyre, Malawi.
Victor MaidenMalawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Dianne J TerlouwMalawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
David G LallooLiverpool School of Tropical Medicine, Liverpool, United Kingdom.
Saye H KhooUniversity of Liverpool, Liverpool, United Kingdom.
Victor MwapasaMalawi College of Medicine, Blantyre, Malawi cgbanda@mlw.mw vmwapasa@medcol.mw.
University of Liverpool · GBLiverpool School of Tropical Medicine · GBUniversity of Malawi · MW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are limited data on the pharmacokinetic and safety profiles of artesunate-amodiaquine in human immnunodeficiency virus-infected (HIV

Indexed as

AdultAmodiaquineAnti-HIV AgentsAntimalarialsArtemisininsDrug CombinationsDrug InteractionsDrug Therapy, CombinationFemaleHIV InfectionsHumansLopinavirMalaria, FalciparumMalawiMaleNevirapineAmodiaquineamodiaquine, artesunate drug combinationAnti-HIV AgentsAntimalarialsArtemisininsdesethylamodiaquineDrug CombinationsLopinavirlopinavir-ritonavir drug combinationNevirapineRitonaviramodiaquineantiretroviral therapymalarianevirapineritonavir-boosted lopinavir

Identifiers

PMID29760133
PMCPMC6021620
OpenAlexW2802436821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.