Evidence map›Paper›PMID 29760045›Full record

ArticleCancer research2018

Weiruo Zhang, Gina Bouchard, Alice Yu, Majid Shafiq, Mehran Jamali, Joseph B Shrager, Kelsey Ayers, Shaimaa Bakr, Andrew J Gentles, Maximilian Diehn and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Multiple pathways of CD34Cell death and differentiation · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Respiratory research · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Weiruo ZhangDepartment of Radiology, Stanford University School of Medicine, Stanford, California.
Gina BouchardDepartment of Radiology, Stanford University School of Medicine, Stanford, California.
Alice YuDepartment of Radiology, Stanford University School of Medicine, Stanford, California.
Majid ShafiqDepartment of Radiology, Stanford University School of Medicine, Stanford, California.
Mehran JamaliDepartment of Radiology, Stanford University School of Medicine, Stanford, California.
Joseph B ShragerDivision of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.
Kelsey AyersDepartment of Radiology, Stanford University School of Medicine, Stanford, California.
Shaimaa BakrDepartment of Electrical Engineering, Stanford University, Stanford, California.
Andrew J GentlesDepartment of Biomedical Data Science, Stanford University School of Medicine, Stanford, California.
Maximilian DiehnDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Andrew QuonDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Robert B WestDepartment of Pathology, Stanford University School of Medicine, Stanford, California.
Viswam NairCanary Center at Stanford for Cancer Early Detection, Palo Alto, California.
Matt van de RijnDepartment of Pathology, Stanford University School of Medicine, Stanford, California.
Sandy NapelDepartment of Radiology, Stanford University School of Medicine, Stanford, California.
Sylvia K PlevritisDepartment of Radiology, Stanford University School of Medicine, Stanford, California. sylvia.plevritis@stanford.edu.
Stanford University · USVA Palo Alto Health Care System · US

Funding

POSTDOCTORAL TRAINING IN MEDICAL INFORMATION SCIENCEST15LM007033 · NLM · STANFORD UNIVERSITY · PI SYLVIA KATINA PLEVRITIS · 1985 to 2026
$25.5M
Spatial-Genomic Integrative Multi-Species Analysis of Lymph Node MetastasisU54CA209971 · NCI · STANFORD UNIVERSITY · PI NOLAN, GARRY P, PLEVRITIS, SYLVIA KATINA · 2016 to 2021
$11.0M
Qualification and Deployment of Imaging Biomarkers of Cancer Treatment ResponseU01CA190214 · NCI · STANFORD UNIVERSITY · PI RUBIN, DANIEL L · 2015 to 2020
$3.1M
Tools for Linking and Mining image and Genomic Data in Non-Small Cell Lung CancerR01CA160251 · NCI · STANFORD UNIVERSITY · PI NAPEL, SANDY A., PLEVRITIS, SYLVIA KATINA · 2011 to 2015
$2.9M
Computing, Optimizing, and Evaluating Quantitative Cancer Imaging BiomarkersU01CA187947 · NCI · STANFORD UNIVERSITY · PI NAPEL, SANDY A., RUBIN, DANIEL L · 2015 to 2019
$2.9M
Clinically-Relevant Regulatory Networks in the Lung Tumor MicroenvironmentU01CA154969 · NCI · STANFORD UNIVERSITY · PI CLARKE, MICHAEL, PLEVRITIS, SYLVIA KATINA · 2011 to 2015
$2.8M
Cancer Systems Biology Scholars ProgramR25CA180993 · NCI · STANFORD UNIVERSITY · PI PLEVRITIS, SYLVIA KATINA · 2014 to 2018
$2.2M
NCI NIH HHS R01 CA160251NCI NIH HHS R25 CA180993NCI NIH HHS U01 CA154969NCI NIH HHS U01 CA187947NCI NIH HHS U01 CA190214NCI NIH HHS U54 CA209971NLM NIH HHS T15 LM007033
6 · The paper itself

Abstract

Metabolic reprogramming of the tumor microenvironment is recognized as a cancer hallmark. To identify new molecular processes associated with tumor metabolism, we analyzed the transcriptome of bulk and flow-sorted human primary non-small cell lung cancer (NSCLC) together with

Indexed as

Adenocarcinoma of LungAgedAged, 80 and overCancer-Associated FibroblastsCarcinoma, Non-Small-Cell LungCell Line, TumorFemaleFluorodeoxyglucose F18Follow-Up StudiesGene Expression ProfilingGlucose Transporter Type 1Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)GlycolysisGlycosylationHexosaminesHumansFluorodeoxyglucose F18GFPT2 protein, humanGlucose Transporter Type 1Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)HexosaminesSLC2A1 protein, human

Identifiers

PMID29760045
PMCPMC6030462
OpenAlexW2803742486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.