ArticleCMAJ open2018
Missed opportunities for prevention of vertical HIV transmission in Canada, 1997-2016: a surveillance study.
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Article in CMAJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 22 citations in OpenAlex.
- Perinatal and early infant outcomes after first-versus second-generation integrase strand transfer inhibitor use in pregnancy.HIV medicine · 2026Article
- La réduction du risque d'infection périnatale chez les nouveau-nés de mères dont les soins prénatals étaient inappropriés.Paediatrics & child health · 2023Review
- Reducing perinatal infection risk in newborns of mothers who received inadequate prenatal care.Paediatrics & child health · 2023Review
- A two-day workshop reviewing Canadian provincial and national HIV care cascade indicators, reporting, challenges, and recommendations.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022Article
- HIV in Canada-surveillance report, 2019.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021Article
- Determinants of Adherence to National Infant Feeding Guidelines by Black Mothers Living with HIV.Ethnicity & disease · 2021Article
- Examination of a Canadian provincial prenatal HIV screening program: 2010 to 2014.Canadian journal of public health = Revue canadienne de sante publique · 2020Article
- HIV in Canada-Surveillance Report, 2017.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Ari BitnunAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Terry LeeAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Jason BrophyAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Lindy M SamsonAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Fatima KakkarAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Wendy VaudryAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Ben TanAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Deborah M MoneyAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Joel SingerAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Laura J SauvéAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Ariane AlimentiAffiliations: Department of Pediatrics (Bitnun), The Hospital for Sick Children, University of Toronto, Toronto, Ont.; Canadian Institutes of Health Research Canadian HIV Trials Network (Lee, Singer), Vancouver, BC; Department of Pediatrics (Brophy, Samson), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Department of Pediatrics (Kakkar), Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montréal, Que.; Department of Pediatrics (Vaudry), Stollery Children's Hospital, University of Alberta, Edmonton, Alta.; Department of Pediatrics (Tan), Royal University Hospital, University of Saskatchewan, Saskatoon, Sask.; Department of Obstetrics & Gynecology (Money), BC Women's Hospital and Health Centre; School of Population and Public Health (Singer); Oak Tree Clinic (Money, Sauvé, Alimenti), BC Women's Hospital and Health Centre, University of British Columbia; Department of Pediatrics, University of British Columbia, Vancouver, BC (Sauvé, Alimenti).
Canadian Perinatal HIV Surveillance Program
Children's Hospital of Eastern Ontario · CAB.C. Women's Hospital & Health Centre · CACanadian Institutes of Health Research · CASinger (United States) · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVertical HIV transmission has declined in Canada, but missed opportunities for prevention continue to occur. We sought to determine the adequacy, and changes over time in adequacy, of uptake of maternal and neonatal antiretroviral therapy for the prevention of vertical HIV transmission, and to determine the vertical transmission rate over time and according to adequacy of antenatal antiretroviral therapy during the combination antiretroviral therapy era in Canada.
methodsThe Canadian Perinatal HIV Surveillance Program collects data annually through retrospective chart review concerning HIV-infected women and their infants. We determined receipt of adequate antiretroviral treatment (antenatal combination antiretroviral treatment for ≥ 4 wk, intrapartum intravenous zidovudine treatment and 4-6 wk of infant oral zidovudine treatment) and predictors of inadequate antenatal combination antiretroviral therapy (none or < 4 wk) in Canada in 1997-2016.
resultsWe identified 3785 mother-infant pairs. Uptake of 4 weeks or more of antenatal combination antiretroviral therapy increased over time across all provinces/territories and regardless of maternal race/ethnicity or risk category (
interpretationEfforts to improve timely access to care, HIV screening and treatment for all women, combined with enhanced resources targeting populations at increased risk for HIV infection, will be needed if vertical HIV transmission is to be eliminated in Canada.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.