SynthesisJACC. Clinical electrophysiology2017
Ablation of Inappropriate Sinus Tachycardia: A Systematic Review of the Literature.
Synthesis in JACC. Clinical electrophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Translational Anatomy of the Sinoatrial Node: Myoarchitecture and its Relevance for Catheter Ablation: Part II: Clinical Applications.JACC. Case reports · 2025Article
- Refractory inappropriate sinus tachycardia post sinus node sparing hybrid thoracoscopic ablation originating from the arcuate ridge.HeartRhythm case reports · 2025Article
- Immunotherapies for postural orthostatic tachycardia syndrome, other common autonomic disorders, and Long COVID: current state and future direction.Frontiers in cellular and infection microbiology · 2025Review
- Robotic-enhanced hybrid ablation for inappropriate sinus tachycardia: a world-first approach.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Article
- Hybrid epicardial and endocardial sinus node-sparing ablation therapy for inappropriate sinus tachycardia: Rationale and design of the multicenter HEAL-IST IDE trial.Heart rhythm O2 · 2023Article
- Cost-utility analysis of radiofrequency ablation versus optimal medical therapy in managing supraventricular tachycardia among Filipinos.Journal of arrhythmia · 2023Article
- Three-dimensional functional anatomy of the human sinoatrial node for epicardial and endocardial mapping and ablation.Heart rhythm · 2023Review
- Sinus Tachycardia: a Multidisciplinary Expert Focused Review.Circulation. Arrhythmia and electrophysiology · 2022Review
- Respiratory variability of sinus node activation in humans: insights from ultra-high-density mapping.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022Article
- Novel SuperMap feature of dipole charge density mapping technique offers advantages for redo catheter ablation in highly symptomatic patients with inappropriate sinus tachycardia: A case series.Clinical case reports · 2021Article
- Long-term outcomes of sinus node modification in patients with severely symptomatic drug-refractory inappropriate sinus tachycardia: a single-center experience.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021Article
- JCS/JHRS 2019 guideline on non-pharmacotherapy of cardiac arrhythmias.Journal of arrhythmia · 2021Article
- Phrenic nerve preservation using carbon dioxide insufflation during sinus node ablation procedure.HeartRhythm case reports · 2021Article
- Combined Epicardial and Endocardial Sinus Node Modification Using the Orion™ Mini-basket Mapping Catheter.The Journal of innovations in cardiac rhythm management · 2021Article
- Structural and Functional Properties of Subsidiary Atrial Pacemakers in a Goat Model of Sinus Node Disease.Frontiers in physiology · 2021Article
- Catheter ablation for inappropriate sinus tachycardia: Clinical outcomes of sinus node ablation.HeartRhythm case reports · 2020Article
- Demonstration of the Anatomical Tachycardia Circuit in Sinoatrial Node Reentrant Tachycardia: Analysis Using the Entrainment Method.Journal of the American Heart Association · 2020Article
- A young female patient with recurrent paroxysms of inappropriate sinus tachycardia.Journal of family medicine and primary care · 2019Article
- Patient Selection for Epicardial Ablation-Part I: The Role of Epicardial Ablation in Various Cardiac Disease States.The Journal of innovations in cardiac rhythm management · 2019Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
objectivesThe goal of this study was to describe short- and long-term outcomes in all patients referred for inappropriate sinus tachycardia ablation, along with the potential complications of the intervention.
backgroundSinus node (SN) ablation/modification has been proposed for patients refractory to pharmacological therapy. However, available data derive from limited series.
methodsThe electronic databases MEDLINE, Embase, CINAHL, Cochrane, and Scopus were systematically searched (January 1, 1995-December 31, 2015). Studies were screened according to predefined inclusion and exclusion criteria.
resultsA total of 153 patients were included. Their mean age was 35.18 ± 10.02 years, and 139 (90.8%) were female. All patients had failed to respond to maximum tolerated doses of pharmacological therapy (3.5 ± 2.4 drugs). Mean baseline heart rates averaged 101.3 ± 16.4 beats/min according to electrocardiography and 104.5 ± 13.5 beats/min according to 24-h Holter monitoring. Two electrophysiological strategies were used, SN ablation and SN modification, with the latter being used more. Procedural acute success (using variably defined pre-determined endpoints) was 88.9%. Consistently, all groups reported high-output pacing from the ablation catheter to confirm absence of phrenic nerve stimulation before radiofrequency delivery. Need of pericardial access varied between 0% and 76.9%. Thirteen patients (8.5%) experienced severe procedural complications, and 15 patients (9.8%) required implantation of a pacemaker. At a mean follow-up interval of 28.1 ± 12.6 months, 86.4% of patients demonstrated successful outcomes. The symptomatic recurrence rate was 19.6%, and 29.8% of patients continued to receive antiarrhythmic drug therapy after procedural intervention.
conclusionsInappropriate sinus tachycardia ablation/modification achieves acute success in the vast majority of patients. Complications are fairly common and diverse. However, symptomatic relief decreases substantially over longer follow-up periods, with a corresponding high recurrence rate.
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