ReviewClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis2018
The Double Hazard of Bleeding and Thrombosis in Hemostasis From a Clinical Point of View: A Global Assessment by Rotational Thromboelastometry (ROTEM).
Review in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 49 citations in OpenAlex.
- Risk factors for massive postoperative bleeding after orthotopic heart transplantation: a retrospective cohort study.Journal of cardiothoracic surgery · 2026Article
- ECMO decannulation is associated with dynamic changes in coagulation profiles: an exploratory, nested cohort study.BMC anesthesiology · 2026Observational
- Alterations in clot microstructure in acute exacerbations of COPD.Respiratory research · 2025Article
- Unveiling the Hemostatic Signature of Prematurity: A Prospective Rotational Thromboelastometry-Based Analysis.Medicina (Kaunas, Lithuania) · 2025Article
- Redefining haemostasis: Role of rotational thromboelastometry in critical care settings.World journal of critical care medicine · 2025Review
- Thromboinflammation vs. immunothrombosis: strategies for overcoming anticoagulant resistance in COVID-19 and other hyperinflammatory diseases. Is ROTEM helpful or not?Frontiers in immunology · 2025Review
- Observational
- Platelet Proteome Reveals Novel Targets for Hypercoagulation in Pseudoexfoliation Syndrome.International journal of molecular sciences · 2024Article
- Cryopreserved Platelets in a Non-Toxic DMSO-Free Solution Maintain Hemostatic Function In Vitro.International journal of molecular sciences · 2023Article
- Is ROTEM Diagnostic in Trauma Care Associated with Lower Mortality Rates in Bleeding Patients?-A Retrospective Analysis of 7461 Patients Derived from the TraumaRegister DGUJournal of clinical medicine · 2022Article
- Evaluation of novel coagulation and platelet function assays in patients with chronic kidney disease.Journal of thrombosis and haemostasis : JTH · 2022Article
- Pragmatic study of a thromboprophylaxis algorithm in critically ill patients with SARS-COV-2 infection.Journal of thrombosis and thrombolysis · 2022Article
- Hypercoagulation Detected by Rotational Thromboelastometry Predicts Mortality in COVID-19: A Risk Model Based on a Prospective Observational Study.TH open : companion journal to thrombosis and haemostasis · 2022Article
- Effect of hyperparathyroidism on coagulation: a global assessment by modified rotation thromboelastogram (ROTEM)Turkish journal of medical sciences · 2021Article
- Thromboelastometry assessment of hemostatic properties in various murine models with coagulopathy and the effect of factor VIII therapeutics.Journal of thrombosis and haemostasis : JTH · 2021Article
- How Can Rotational Thromboelastometry as a Point-of-Care Method Be Useful for the Management of Secondary Thromboprophylaxis in High-Risk Pregnant Patients?Diagnostics (Basel, Switzerland) · 2021Article
- Thromboelastography-Guided Anticoagulant Therapy for the Double Hazard of Thrombohemorrhagic Events in COVID-19: A Report of 3 Cases.The American journal of case reports · 2021Article
- Rotational thromboelastometry to assess hypercoagulability in COVID-19 patients.Thrombosis research · 2020Article
- Evaluation of coagulation function by rotation thromboelastometry in critically ill patients with severe COVID-19 pneumonia.Journal of thrombosis and thrombolysis · 2020Observational
- Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hemostasis is a complex dynamic process involving bleeding and thrombosis as two end-points. Conventional coagulation tests which are measured in plasma examine only isolated portions of the coagulation cascade, thereby giving no information on important interactions essential to the clinical evaluation of hemostatic function. Thromboelastography (TEG), originally described in 1948 has improved over the decades and become a valuable tool of coagulation testing because of the limitations of standard coagulation tests. TEG is a technique that provides data about the entire coagulation system, from the beginning of clot formation to fibrinolysis, involving both cellular and plasma components of hemostasis. Rotational thromboelastometry (ROTEM) which evolved from TEG technology overcome several limitations of classical TEG while maintaining a good correlation with conventional TEG determination. ROTEM analyses are useful for rapid assessment of global clotting function in various clinical situations including liver transplantation, cardiac surgery, obstetrics, trauma, hemophilia and idiopathic thrombocytopenic purpura. ROTEM has been also reported to be useful in identifying various hypercoagulable conditions including major surgery, malignancy, Behcet's disease and apheresis. Further developments in ROTEM based transfusion strategies may also reduce transfusion requirements and improve clinical outcomes by optimizing the administration of blood components. This is a literature review of ROTEM including its technique, interpretation and specially clinical applications in different scenarios of bleeding and thrombotic disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.