SynthesisPLoS neglected tropical diseases2018
A systematic review of human and animal leptospirosis in the Pacific Islands reveals pathogen and reservoir diversity.
Synthesis in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 5 of them syntheses that pooled it.
What it found
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Who cites it
51 citing papers in PubMed, 5 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- Drivers of humanEpidemiology and infection · 2024Pooled it
- Global distribution of Leptospira serovar isolations and detections from animal host species: A systematic review and online database.Tropical medicine & international health : TM & IH · 2024Pooled it
- Leptospirosis in humans and selected animals in Sub-Saharan Africa, 2014-2022: a systematic review and meta-analysis.BMC infectious diseases · 2023Pooled it
- A systematic review and meta-analysis of the potential non-human animal reservoirs and arthropod vectors of the Mayaro virus.PLoS neglected tropical diseases · 2021Pooled it
- Risk factors for human leptospirosis following flooding: A meta-analysis of observational studies.PloS one · 2019Pooled it
- A systematic review and meta-analysis ofOne health (Amsterdam, Netherlands) · 2026Review
- Molecular epidemiology of rodent-borneJournal of medical microbiology · 2026Article
- Leptospira licerasiae, a zoonotic pathogen isolated from water sources in Santa Maria, Rio Grande do Sul, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Human leptospirosis in the central division of Fiji: a retrospective epidemiological study.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025Article
- High prevalence and diversity ofOne health (Amsterdam, Netherlands) · 2025Article
- Prevalent Infectious Causes of Abortion in the Ruminant Population in Iran- A Literature Review.Archives of Razi Institute · 2025Review
- Leptospirosis.Nature reviews. Disease primers · 2025Review
- Human animal contact, land use change and zoonotic disease risk: a protocol for systematic review.Systematic reviews · 2025Article
- Spatio-temporal risk prediction of leptospirosis: A machine-learning-based approach.PLoS neglected tropical diseases · 2025Article
- A systematic survey of environmental DNA in Palau's lakes and waterfalls reveals an increase inOne health (Amsterdam, Netherlands) · 2024Article
- Bacteriological and Serological Investigation of Leptospirosis in Dogs and Pigs in Palau.The American journal of tropical medicine and hygiene · 2024Article
- A retrospective study of animal leptospirosis in Kazakhstan.Journal of advanced veterinary and animal research · 2024Article
- Detection of PathogenicAnimals : an open access journal from MDPI · 2024Article
- Climate-driven models of leptospirosis dynamics in tropical islands from three oceanic basins.PLoS neglected tropical diseases · 2024Article
- Pathogenic Leptospira contamination in the environment: a systematic review.Infection ecology & epidemiology · 2024Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 5 countries.
Funding
Abstract
backgroundThe Pacific Islands have environmental conditions highly favourable for transmission of leptospirosis, a neglected zoonosis with highest incidence in the tropics, and Oceania in particular. Recent reports confirm the emergence and outbreaks of leptospirosis in the Pacific Islands, but the epidemiology and drivers of transmission of human and animal leptospirosis are poorly documented, especially in the more isolated and less developed islands. METHODOLOGY/PRINCIPAL
findingsWe conducted a systematic review of human and animal leptospirosis within 25 Pacific Islands (PIs) in Polynesia, Melanesia, Micronesia, as well as Easter Island and Hawaii. We performed a literature search using four international databases for articles published between January 1947 and June 2017. We further included grey literature available on the internet. We identified 148 studies describing leptospirosis epidemiology, but the number of studies varied significantly between PIs. No data were available from four PIs. Human leptospirosis has been reported from 13 PIs, with 63% of all studies conducted in Hawaii, French Polynesia and New Caledonia. Animal leptospirosis has been investigated in 19 PIs and from 14 host species, mainly pigs (18% of studies), cattle (16%) and dogs (11%). Only 13 studies provided information on both human and animal leptospirosis from the same location. Serology results were highly diverse in the region, both in humans and animals. CONCLUSIONS/SIGNIFICANCE: Our study suggests that, as in other tropical regions, leptospirosis is widespread in the PIs while showing some epidemiological heterogeneity. Data are scarce or absent from many PIs. Rodents, cattle, pigs and dogs are all likely to be important carriers, but the relative importance of each animal species in human infection needs to be clarified. Epidemiological surveys with appropriate sampling design, pathogen typing and data analysis are needed to improve our understanding of transmission patterns and to develop effective intervention strategies.
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