Evidence map›Paper›PMID 29758012›Full record

ArticleInternational journal of molecular sciences2018

The Long Non-Coding RNA MIR503HG Enhances Proliferation of Human ALK-Negative Anaplastic Large-Cell Lymphoma.

Po-Shuan Huang, I-Hsiao Chung, Yang-Hsiang Lin, Tzu-Kang Lin, Wei-Jan Chen, Kwang-Huei Lin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

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  17. Non-Coding RNA Networks in ALK-Positive Anaplastic-Large Cell Lymphoma.International journal of molecular sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Po-Shuan HuangDepartment of Biochemistry, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. leo_6813@msn.com.
I-Hsiao ChungDepartment of Biochemistry, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. isiou2007game@gmail.com.
Yang-Hsiang LinDepartment of Biochemistry, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. yhlin0621@cgmh.org.tw.
Tzu-Kang LinNeurosurgery, Fu Jen Catholic University Hospital and School of Medicine, Fu Jen Catholic University, New Taipei City 24250, Taiwan. tklin100@gmail.com.
Wei-Jan ChenCardiovascular Division, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, Taiwan. wjchen@adm.cgmh.org.tw.
Kwang-Huei LinDepartment of Biochemistry, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. khlin@mail.cgu.edu.tw.ORCID 0000-0002-5649-2222
Chang Gung University · TWChang Gung University of Science and Technology · TWFu Jen Catholic University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaplastic lymphoma kinase (ALK)-negative anaplastic large-cell lymphoma (ALCL) is a rare type of highly malignant, non-Hodgkin lymphoma. Currently, only a few gene rearrangements have been linked to ALK-negative ALCL progression. However, the specific molecular mechanisms underlying the growth of ALK-negative ALCL tumors remain unclear. Here, we investigated aberrantly expressed, long non-coding RNAs (lncRNAs) in ALK-negative ALCL and assessed their potential biological function.

Indexed as

Gene Expression Regulation, NeoplasticAnaplastic Lymphoma KinaseAnimalsCell Line, TumorCell ProliferationDisease Models, AnimalHeterograftsHumansLymphoma, Large-Cell, AnaplasticMiceMicroRNAsReceptor Protein-Tyrosine KinasesReceptors, Transforming Growth Factor betaRNA InterferenceRNA, Long NoncodingUbiquitin-Protein LigasesALK protein, humanAlk protein, mouseAnaplastic Lymphoma Kinaselong non-coding RNA MIR503HG, humanMicroRNAsMIRN503 microRNA, humanReceptor Protein-Tyrosine KinasesReceptors, Transforming Growth Factor betaRNA, Long NoncodingSMURF2 protein, humanUbiquitin-Protein LigasesALK-negative ALCLMIR503HGproliferation

Identifiers

PMID29758012
PMCPMC5983830
OpenAlexW2800265975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.