Evidence map›Paper›PMID 29757989›Full record

ArticleMolecules (Basel, Switzerland)2018

Synthesis and Evaluation of Antiplasmodial Activity of 2,2,2-Trifluoroethoxychalcones and 2-Fluoroethoxy Chalcones against Plasmodium falciparum in Culture.

Kavita Devi, Vinoth Rajendran, Ayushee, T M Rangarajan, Rishi Pal Singh, Prahlad C Ghosh, Manjula Singh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kavita DeviFluoroorganic Laboratory, Center for Fire, Explosive and Environment Safety, Delhi-110 054, India. kavik188@gmail.com.
Vinoth RajendranDepartment of Biochemistry, University of Delhi South Campus, Benito Juarez Road, New Delhi 110 021, India. vinoth.avj@gmail.com.ORCID 0000-0003-1453-1139
AyusheeDepartment of Chemistry, Hansraj College, University of Delhi, Delhi 110 007, India. ayusheesingh27@yahoo.in.
T M RangarajanDepartment of Chemistry, Sri Venkateswara College, University of Delhi, New Delhi 110 021, India. rangarajan93150@gmail.com.ORCID 0000-0002-5972-1879
Rishi Pal SinghDepartment of Chemistry, Sri Venkateswara College, University of Delhi, New Delhi 110 021, India. rpsingh54@gmail.com.
Prahlad C GhoshDepartment of Biochemistry, University of Delhi South Campus, Benito Juarez Road, New Delhi 110 021, India. pcghose@gmail.com.
Manjula SinghDepartment of Chemistry, Shivaji College, University of Delhi, New Delhi 110 027, India. manjulasingh56@gmail.com.
University of Delhi · INCentre for Fire, Explosive and Environment Safety · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new class of compounds comprising two series of chalcones with 2,2,2-trifluoroethoxy group and 2-fluoroethoxy groups were synthesized and screened for in vitro antiplasmodial activity against

Indexed as

AnimalsAntimalarialsChalconesChemistry Techniques, SyntheticChlorocebus aethiopsErythrocytesInhibitory Concentration 50Malaria, FalciparumParasitic Sensitivity TestsPlasmodium falciparumVero CellsAntimalarialsChalconesantiplasmodial activityartemisinin combination therapycytotoxicityfluoroethoxychalconesPlasmodium falciparum (3D7)

Identifiers

PMID29757989
PMCPMC6099641
OpenAlexW2801100547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.