Evidence map›Paper›PMID 29757986›Full record

ReviewInternational journal of molecular sciences2018

Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus.

Bahare Salehi, Nanjangud V Anil Kumar, Bilge Şener, Mehdi Sharifi-Rad, Mehtap Kılıç, Gail B Mahady, Sanja Vlaisavljevic, Marcello Iriti, Farzad Kobarfard, William N Setzer and 3 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Prospects ofHeliyon · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. AnFrontiers in pharmacology · 2024
    Article
  12. Dual Effects of 3-International journal of molecular sciences · 2023
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Green Synthesis of Silver Nanoparticles fromPlants (Basel, Switzerland) · 2022
    Article
  20. Potential Active Constituents fromPharmaceuticals (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bahare SalehiMedical Ethics and Law Research Center, Shahid Beheshti University of Medical Sciences, 88777539 Tehran, Iran. bahar.salehi007@gmail.com.ORCID 0000-0002-6900-9797
Nanjangud V Anil KumarDepartment of Chemistry, Manipal Institute of Technology, Manipal University, Manipal 576104, India. nv.anil@manipal.edu.ORCID 0000-0002-8016-8991
Bilge ŞenerDepartment of Pharmacognosy, Gazi University, Faculty of Pharmacy, 06330 Ankara, Turkey. bilgesener11@gmail.com.
Mehdi Sharifi-RadDepartment of Medical Parasitology, Zabol University of Medical Sciences, 61663-335 Zabol, Iran. mehdi_sharifirad@yahoo.com.
Mehtap KılıçDepartment of Pharmacognosy, Gazi University, Faculty of Pharmacy, 06330 Ankara, Turkey. klcmehtap89@gmail.com.
Gail B MahadyPAHO/WHO Collaborating Centre for Traditional Medicine, College of Pharmacy, University of Illinois, 833 S. Wood St., Chicago, IL 60612, USA. g.b.mahady@gmail.com.
Sanja VlaisavljevicDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovica 3, 21000 Novi Sad, Serbia. sanja.vlaisavljevic@dh.uns.ac.rs.
Marcello IritiDepartment of Agricultural and Environmental Sciences, Milan State University, 20133 Milan, Italy. marcello.iriti@unimi.it.ORCID 0000-0002-5063-1236
Farzad KobarfardPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, 11369 Tehran, Iran. farzadkf@yahoo.com.
William N SetzerDepartment of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA. wsetzer@chemistry.uah.edu.
Seyed Abdulmajid AyatollahiPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, 11369 Tehran, Iran. majid_ayatollahi@yahoo.com.
Athar AtaDepartment of Chemistry, Richardson College for the Environmental Science Complex, The University of Winnipeg, Winnipeg, MB R3B 2G3, Canada. a.ata@uwinnipeg.ca.
Javad Sharifi-RadPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, 11369 Tehran, Iran. javad.sharifirad@gmail.com.ORCID 0000-0002-7301-8151

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.

Indexed as

Anti-HIV AgentsBiological ProductsClinical Trials as TopicDrug DiscoveryHIV-1HIV InfectionsHumansPlant ExtractsPlants, MedicinalSecondary MetabolismTreatment OutcomeAnti-HIV AgentsBiological ProductsPlant Extractsacquired immune deficiency syndromeantiviraldrug discoverypharmacognosyphytochemistry

Identifiers

PMID29757986
PMCPMC5983620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.