Evidence map›Paper›PMID 29757959›Full record

ArticleNutrients2018

Association of Genetic Variation in the Epithelial Sodium Channel Gene with Urinary Sodium Excretion and Blood Pressure.

Yoon Jung Yang, Jihye Kim, Chang Keun Kwock

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Epithelial NaComprehensive Physiology · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Yoon Jung YangDepartment of Foods and Nutrition, College of Natural Sciences, Dongduk Women's University, Seoul 02748, Korea. yjyang@dongduk.ac.kr.ORCID 0000-0001-9395-0854
Jihye KimDepartment of Preventive Medicine, College of Medicine, Hanyang University, Seoul 04764, Korea. eluzai81@hanyang.ac.kr.
Chang Keun KwockNutrition and Diet Research Group, Korea Food Research Institute, Jeollabuk-do 55365, Korea. kwock@kfri.re.kr.
Dongduk Women's University · KRHanyang University · KRKorea Food Research Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was performed to investigate whether genetic variation in the epithelial sodium channel (ENaC) is associated with 24-h urinary sodium excretion and blood pressure. A total of 3345 participants of the KoGES_Ansan and Ansung study were eligible for this study. Genomic DNA samples were isolated from peripheral blood and genotyped on the Affymetrix Genome-Wide Human SNP Array 5.0. Thirty-four single nucleotide polymorphisms (SNPs) were extracted for gene regions (

Indexed as

Polymorphism, Single NucleotideAdultAllelesAsian PeopleBlood PressureBody Mass IndexCohort StudiesEpithelial Sodium ChannelsFemaleGenotyping TechniquesHumansMaleMiddle AgedSocioeconomic FactorsSodiumEpithelial Sodium ChannelsSCNN1A protein, humanSCNN1B protein, humanSCNN1G protein, humanSodium24-h urinary sodium excretionblood pressureENaCgenetic variantSCNN1ASCNN1BSCNN1G

Identifiers

PMID29757959
PMCPMC5986492
OpenAlexW2799387734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.