Evidence map›Paper›PMID 29757932›Full record

ArticleInternational journal of molecular sciences2018

SOX7 Target Genes and Their Contribution to Its Tumor Suppressive Function.

Yumeng Zhang, Daniel B Stovall, Meimei Wan, Qiang Zhang, Jeff W Chou, Dangdang Li, Guangchao Sui

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. MTHFD2: a promising metabolic checkpoint for diseases.Journal of translational medicine · 2026
    Review
  2. Review
  3. Genetic and Epigenetic Aberrations ofCurrent issues in molecular biology · 2025
    Article
  4. Alveolar type 2 cells marker geneFrontiers in oncology · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Connection between SOX7 Expression and Breast Cancer Prognosis.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yumeng ZhangCollege of Life Science, Northeast Forestry University, Harbin 150040, Heilongjiang, China. clover_1211@nefu.edu.cn.
Daniel B StovallDivision of Math and Science, North Carolina Wesleyan College, Rocky Mount, NC 27804, USA. dstovall@ncwc.edu.
Meimei WanDepartment of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. mwan@wakehealth.edu.
Qiang ZhangDepartment of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. bioqiang@aliyun.com.
Jeff W ChouDepartment of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. jchou@wakehealth.edu.
Dangdang LiCollege of Life Science, Northeast Forestry University, Harbin 150040, Heilongjiang, China. lidd@nefu.edu.cn.
Guangchao SuiCollege of Life Science, Northeast Forestry University, Harbin 150040, Heilongjiang, China. gcsui@nefu.edu.cn.
Wake Forest University · USNortheast Forestry University · CNNorth Carolina Wesleyan College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SOX7 is a transcription factor and acts as a tumor suppressor, but its target genes in cancers are poorly explored. We revealed SOX7-mediated gene expression profile in breast cancer cells using microarray chips and discovered multiple altered signaling pathways. When combinatorially analyzing the microarray data with a gene array dataset from 759 breast cancer patients, we identified four genes as potential targets of SOX7 and validated them by quantitative PCR and chromatin immunoprecipitation assays. Among these four genes, we determined that SOX7-activated

Indexed as

Gene Expression Regulation, NeoplasticBreast NeoplasmsCell Line, TumorFemaleGene ExpressionGene Expression ProfilingGenes, ReporterHumansProtein BindingReproducibility of ResultsSOXF Transcription FactorsTranscriptomeTumor Suppressor ProteinsSOX7 protein, humanSOXF Transcription FactorsTumor Suppressor Proteinsbreast cancercell proliferationgene expression arraySOX7target genes

Identifiers

PMID29757932
PMCPMC5983648
OpenAlexW2802887171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.