Evidence map›Paper›PMID 29757686›Full record

SynthesisJournal of clinical oncology : official journal of the American Society of Clinical Oncology2018

Predictors of Unemployment After Breast Cancer Surgery: A Systematic Review and Meta-Analysis of Observational Studies.

Li Wang, Brian Y Hong, Sean A Kennedy, Yaping Chang, Chris J Hong, Samantha Craigie, Henry Y Kwon, Beatriz Romerosa, Rachel J Couban, Susan Reid and 4 more

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Prognostic factors for return to work in breast cancer survivors.The Cochrane database of systematic reviews · 2025
    Pooled it
  5. Pooled it
  6. Return to Work Interventions for Cancer Survivors: A Systematic Review and a Methodological Critique.International journal of environmental research and public health · 2019
    Pooled it
  7. Trial
  8. Article
  9. Observational
  10. Article
  11. Socioeconomic differences in labour market attachment after breast cancer: a population-based matched cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Gender differences in employment disruption and return to work among cancer survivors in South Korea.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Li WangLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Brian Y HongLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Sean A KennedyLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Yaping ChangLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Chris J HongLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Samantha CraigieLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Henry Y KwonLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Beatriz RomerosaLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Rachel J CoubanLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Susan ReidLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
James S KhanLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Michael McGillionLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Victoria BlinderLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.
Jason W BusseLi Wang, Yaping Chang, Samantha Craigie, Rachel J. Couban, Susan Reid, Michael McGillion, and Jason W. Busse, McMaster University, Hamilton; Sean A. Kennedy and Chris J. Hong, University of Toronto, Toronto; Brian Y. Hong, University of Ottawa, Ottawa, Ontario, Canada; Li Wang, West China Hospital, Sichuan University, Chengdu, People's Republic of China; Henry Y. Kwon, Wayne State University School of Medicine, Detroit, MI; Beatriz Romerosa, University Hospital of Toledo, Toledo, Spain; James S. Khan, Stanford University, Palo Alto, CA; and Victoria Blinder, Memorial Sloan Kettering Cancer Center, New York, NY.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Purpose Breast cancer surgery is associated with unemployment. Identifying high-risk patients could help inform strategies to promote return to work. We systematically reviewed observational studies to explore factors associated with unemployment after breast cancer surgery. Methods We searched MEDLINE, EMBASE, CINAHL, and PsycINFO to identify studies that explored risk factors for unemployment after breast cancer surgery. When possible, we pooled estimates of association for all independent variables reported by more than one study. Results Twenty-six studies (46,927 patients) reported the association of 127 variables with unemployment after breast cancer surgery. Access to universal health care was associated with higher rates of unemployment (26.6% v 15.4%; test of interaction P = .05). High-quality evidence showed that unemployment after breast cancer surgery was associated with high psychological job demands (odds ratio [OR], 4.26; 95% CI, 2.27 to 7.97), childlessness (OR, 1.30; 95% CI, 1.11 to 1.53), lower education level (OR, 1.15; 95% CI, 1.05 to 1.25), lower income level (OR, 1.46; 95% CI, 1.24 to 1.73), cancer stage II, III or IV (OR, 1.43; 95% CI, 1.13 to 1.82), and mastectomy versus breast-conserving surgery (OR, 1.18; 95% CI, 1.07 to 1.30). Moderate-quality evidence suggested an association with high physical job demands (OR, 2.11; 95%CI, 1.52 to 2.93), African-American ethnicity (OR, 1.89; 95% CI, 1.21 to 2.96), and receipt of chemotherapy (OR, 1.95; 95% CI, 1.36 to 2.79). High-quality evidence demonstrated no significant association with part-time hours, blue-collar work, tumor size, positive lymph nodes, or receipt of radiotherapy or endocrine therapy; moderate-quality evidence suggested no association with age, marital status, or axillary lymph node dissection. Conclusion Addressing high physical and psychological job demands may be important in reducing unemployment after breast cancer surgery.

Indexed as

BiasBreast NeoplasmsCase-Control StudiesCohort StudiesHumansObservational Studies as TopicPrevalenceSocioeconomic FactorsUnemployment

Identifiers

PMID29757686
PMCPMC6804906

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.