Evidence map›Paper›PMID 29757142›Full record

ArticleeLife2018

Autistic traits, but not schizotypy, predict increased weighting of sensory information in Bayesian visual integration.

Povilas Karvelis, Aaron R Seitz, Stephen M Lawrie, Peggy Seriès

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Reduced Dissociation Between Perception and Action in Autistic Individuals.Journal of autism and developmental disorders · 2026
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  13. Disentangling the perceptual underpinnings of autism: Evidence from a face aftereffects experiment.Autism research : official journal of the International Society for Autism Research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Povilas KarvelisIANC, School of Informatics, University of Edinburgh, Edinburgh, United Kingdom.
Aaron R SeitzDepartment of Psychology, UC Riverside, Riverside, United States.
Stephen M LawrieDivision of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0002-2444-5675
Peggy SerièsIANC, School of Informatics, University of Edinburgh, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0002-8580-7975

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent theories propose that schizophrenia/schizotypy and autistic spectrum disorder are related to impairments in Bayesian inference that is, how the brain integrates sensory information (likelihoods) with prior knowledge. However existing accounts fail to clarify: (i) how proposed theories differ in accounts of ASD vs. schizophrenia and (ii) whether the impairments result from weaker priors or enhanced likelihoods. Here, we directly address these issues by characterizing how 91 healthy participants, scored for autistic and schizotypal traits, implicitly learned and combined priors with sensory information. This was accomplished through a visual statistical learning paradigm designed to quantitatively assess variations in individuals' likelihoods and priors. The acquisition of the priors was found to be intact along both traits spectra. However, autistic traits were associated with more veridical perception and weaker influence of expectations. Bayesian modeling revealed that this was due, not to weaker prior expectations, but to more precise sensory representations.

Indexed as

Models, NeurologicalVisual PerceptionAdolescentAdultAgedAutistic DisorderFemaleHumansLearningMaleMiddle AgedMotivationSchizotypal Personality DisorderYoung AdultautismBayesian cognitioncomputational psychiatryhumanneuroscienceschizophrenia

Identifiers

PMID29757142
PMCPMC5966274

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.