ArticleChronic diseases and translational medicine2018
Very low-protein diet to postpone renal failure: Pathophysiology and clinical applications in chronic kidney disease.
Article in Chronic diseases and translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- A Meta-Analysis Examining the Impact of Consuming Nitrogen-Free Analogs of Essential Amino Acids on the Progression of Chronic Renal Disease.Medicina (Kaunas, Lithuania) · 2025Pooled it
- The Effect of Ketoanalogues on Chronic Kidney Disease Deterioration: A Meta-Analysis.Nutrients · 2019Pooled it
- The impact of beverage consumption on chronic renal failure risk and the mediation of serum metabolites: based on Mendelian randomization study.Genes & nutrition · 2025Article
- A practical approach to nutritional intervention for people with chronic kidney disease in Vietnam.Asia Pacific journal of clinical nutrition · 2024Article
- Exercise intolerance in kidney diseases: physiological contributors and therapeutic strategies.American journal of physiology. Renal physiology · 2021Review
- Diet and Skin Aging-From the Perspective of Food Nutrition.Nutrients · 2020Review
- Dialysis Reimbursement: What Impact Do Different Models Have on Clinical Choices?Journal of clinical medicine · 2019Article
- Very low protein diet plus ketoacid analogs of essential amino acids supplement to retard chronic kidney disease progression.Kidney research and clinical practice · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The uremic syndrome is a metabolic disorder characterized by the impairment of renal handling of several solutes, the resulting accumulation of toxic products and the activation of some adaptive but detrimental mechanisms which all together contribute to the progression of renal damage. In moderate to advanced renal failure, the dietary manipulation of nutrients improves metabolic abnormalities and may contribute to delay the time of dialysis initiation. This commentary focuses on the physiopathological rationale and the clinical application of the very low-protein diet supplemented with ketoanalogs for the management of chronic kidney disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.