Postoperative opioids, endocrine changes, and immunosuppression.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

17 citing papers in PubMed.

1. Comparison of Postoperative Pain Following Modified Radical Mastectomy under Thoracic Epidural Anesthesia versus General Anesthesia: A Randomized Control Trial.Annals of African medicine · 2026
   Trial
2. Rationale and design of the SMILe (Spinal Morphine or Intravenous Lidocaine) study: protocol for a multicentre randomised clinical trial in southern Sweden on whether spinal morphine improves postoperative recovery compared to intravenous lidocaine in patients undergoing robot-assisted upper urinary tract surgery.BMJ open · 2026
   Article
3. Opioid-Induced Constipation: Mechanistic Insights, Experimental Models, and Future Perspectives.Biomedicines · 2026
   Review
4. Investigating the role of opium consumption in the severity, and outcome of COVID-19.BMC infectious diseases · 2026
   Article
5. Comparison of Effects of General Versus Spinal Anesthesia on Spermiogram Parameters and Pregnancy Rates After Microscopic Subinguinal Varicocelectomy Surgery: Retrospective Cohort Analysis.Medicina (Kaunas, Lithuania) · 2026
   Article
6. Erector Spinae Plane Block for Percutaneous Transhepatic Biliary Drainage: A Comparative Analysis.Cardiovascular and interventional radiology · 2025
   Article
7. Prenatal alcohol exposure promotes nerve injury-induced pathological pain following morphine treatment via NLRP3-mediated peripheral and central proinflammatory immune actions.Brain, behavior, and immunity · 2025
   Article
8. Causes and management of acute oncological pain: a narrative review.Anaesthesia · 2025
   Review
9. Risk of infections among persons treated with opioids for chronic pain: a systematic review and meta-analysis protocol.BMJ open · 2024
   Article
10. The Surgical Stress Response and Anesthesia: A Narrative Review.Journal of clinical medicine · 2024
    Review
11. Effect of Intraoperative Opioid Dose on Perioperative Neutrophil-to-Lymphocyte Ratio and Lymphocyte-to-Monocyte Ratio in Glioma.Journal of inflammation research · 2024
    Article
12. Ultrasound assessment of residual gastric volume in older adults undergoing staged-bilateral total knee arthroplasty after consuming carbohydrate-containing fluids: a prospective observational study.Korean journal of anesthesiology · 2023
    Observational
13. Effect of epidural analgesia on long-term outcomes after curative surgery for pancreatic cancer: A single-center cohort study in Taiwan.Journal of the Chinese Medical Association : JCMA · 2022
    Article
14. Continuous wound infusion with ropivacaine alone provides adequate analgesia following laparotomy.Langenbeck's archives of surgery · 2021
    Article
15. Morphine-mediated release of miR-138 in astrocyte-derived extracellular vesicles promotes microglial activation.Journal of extracellular vesicles · 2020
    Article
16. Management of Opioid-Tolerant Patients with Acute Pain: Approaching the Challenges.Drugs · 2020
    Review
17. Opioid-induced immunosuppression and carcinogenesis promotion theories create the newest trend in acute and chronic pain pharmacotherapy.Clinics (Sao Paulo, Brazil) · 2020
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract