Evidence map›Paper›PMID 29756011›Full record

ArticleEndoscopy international open2018

Transoral incisional fundoplication for reflux after peroral endoscopic myotomy: a crucial addition to our arsenal.

Amy Tyberg, Anthony Choi, Monica Gaidhane, Michel Kahaleh

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Endoscopy international open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Guideline
  2. Peroral endoscopic myotomyWorld journal of gastroenterology · 2022
    Trial
  3. Article
  4. Prevention, detection and management of adverse events of third-space endoscopy.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Third-space endoscopy: the final frontier.Gastroenterology report · 2023
    Review
  13. Review
  14. Article
  15. POEM, GPOEM, and ZPOEM.Digestive diseases and sciences · 2022
    Review
  16. Endoscopic Management of GERD.Digestive diseases and sciences · 2022
    Review
  17. Peroral endoscopic longerWorld journal of gastrointestinal surgery · 2022
    Article
  18. Article
  19. Article
  20. The Modern Age of POEM: the Past, Present and Future of Per-Oral Endoscopic Myotomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amy TybergRutgers Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ USA.
Anthony ChoiRutgers Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ USA.
Monica GaidhaneRutgers Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ USA.
Michel KahalehRutgers Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ USA.
Rutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIncreased esophageal acid exposure is seen in a large percentage of patients with achalasia who undergo peroral endoscopic myotomy (POEM). Endoscopic transoral fundoplication (TIF) is a novel endoscopic technique for the management of patients with chronic gastroesophageal reflux (GERD). We present the first case series evaluating the role of TIF post-POEM.

methodsConsecutive patients 18 years or older from our academic institution who underwent a POEM procedure and subsequently underwent TIF for symptomatic reflux or regurgitation between December 2014 and June 2017 were included. The primary outcome was discontinuation of proton-pump inhibitor (PPI) use and healing of esophagitis (when initially present) on post-procedure esophagogastroduodenoscopy (EGD). Technical success was defined as successful completion of the endoscopic fundoplication. Adverse events (AEs) were recorded for all patients.

resultsFive patients were included (60 % male, average age 55 ± 14 years). Technical success was achieved in 100 % of patients. Discontinuation of PPI use was achieved in 5/5 patients (100 %). Three patients had esophagitis pre-procedure and all were noted to have resolution of inflammation on post-procedure EGD. No adverse events were noted. Mean follow-up time was 27 months (range 5 - 34 months).

conclusionTIF post-POEM appears feasible, safe, and efficacious in improving symptoms and esophagitis, decreasing long-term risks of acid exposure, and decreasing risks of long-term PPI use in patients post-POEM in this small cohort of patients. Larger studies are needed to confirm these initial findings.

Identifiers

PMID29756011
PMCPMC5943699
OpenAlexW2801686887

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.