Evidence map›Paper›PMID 29755967›Full record

ReviewFrontiers in chemistry2018

Metal-Mediated Halogen Exchange in Aryl and Vinyl Halides: A Review.

Gwilherm Evano, Antoine Nitelet, Pierre Thilmany, Damien F Dewez

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. 1,3-Disilabicyclo[1.1.0]butane and ηInorganic chemistry · 2026
    Article
  3. Nitrosonium Ion-Catalyzed Oxidative Chlorination of Arenes.The Journal of organic chemistry · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Direct Mechanocatalytic Suzuki-Miyaura Reaction of Small Organic Molecules.Angewandte Chemie (International ed. in English) · 2022
    Article
  10. Review
  11. Article
  12. Review
  13. A Protecting-Group-Free Synthesis of (-)-Salvinorin A.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  14. Site Selective Chlorination of C(spAngewandte Chemie (International ed. in English) · 2021
    Article
  15. Nickel-Catalyzed Conversion of Enol Triflates into Alkenyl Halides.Angewandte Chemie (International ed. in English) · 2019
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gwilherm EvanoLaboratoire de Chimie Organique, Service de Chimie et PhysicoChimie Organiques, Université libre de Bruxelles, Brussels, Belgium.
Antoine NiteletLaboratoire de Chimie Organique, Service de Chimie et PhysicoChimie Organiques, Université libre de Bruxelles, Brussels, Belgium.
Pierre ThilmanyLaboratoire de Chimie Organique, Service de Chimie et PhysicoChimie Organiques, Université libre de Bruxelles, Brussels, Belgium.
Damien F DewezLaboratoire de Chimie Organique, Service de Chimie et PhysicoChimie Organiques, Université libre de Bruxelles, Brussels, Belgium.
Université Libre de Bruxelles · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Halogenated arenes and alkenes are of prime importance in many areas of science, especially in the pharmaceutical, agrochemical, and chemical industries. While the simplest ones are commercially available, some of them are still hardly accessible depending on their substitution patterns and the nature of the halogen atom. Reactions enabling the selective and efficient replacement of the halogen atom of an aryl or alkenyl halide by another one, lighter, or heavier, are therefore of major importance since they can be used for example to turn a less reactive aryl/alkenyl chloride into the more reactive iodinated derivatives or, in a reversed sense, to block an undesired reactivity, for late-stage modifications or for the introduction of a radionuclide. If some halogen exchange reactions are possible with activated substrates, they usually require catalysis with metal complexes. Remarkably efficient processes have been developed for metal-mediated halogen exchange in aryl and vinyl halides: they are overviewed, in a comprehensive manner, in this review article.

Indexed as

aryl fluoridesaryl halidescatalysisfinkelsteinhalogen exchangevinyl halides

Identifiers

PMID29755967
PMCPMC5932166
OpenAlexW2795008817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.