Evidence map›Paper›PMID 29755936›Full record

ArticleBiomedical spectroscopy and imaging2017

Phase-encoded single-voxel magnetic resonance spectroscopy for suppressing outer volume signals at 7 Tesla.

Ningzhi Li, Li An, Christopher Johnson, Jun Shen

Abstract read
In one paragraph

Article in Biomedical spectroscopy and imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Identifying out-of-voxel echoes in edited MRS with phase cycle inversion.bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ningzhi LiMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Li AnMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Christopher JohnsonMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Jun ShenMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.

Funding

Intramural NIH HHS Z99 MH999999
6 · The paper itself

Abstract

backgroundDue to imperfect slice profiles, unwanted signals from outside the selected voxel may significantly contaminate metabolite signals acquired using in vivo magnetic resonance spectroscopy (MRS). The use of outer volume suppression may exceed the SAR threshold, especially at high field.

objectiveWe propose using phase-encoding gradients after radiofrequency (RF) excitation to spatially encode unwanted signals originating from outside of the selected single voxel.

methodsPhase-encoding gradients were added to a standard single voxel point-resolved spectroscopy (PRESS) sequence which selects a 2 × 2 × 2 cm

resultsBoth phantom and in vivo studies showed that spectra from the phase-encoded PRESS sequence were relatively immune from contamination by oil signals and have more accurate quantification results than spectra from standard PRESS spectra of the same voxel.

conclusionThe proposed phase-encoded single-voxel PRESS method can significantly suppress outer volume signals that may appear in the spectra of standard PRESS without increasing RF power deposition.

Indexed as

high fieldlipid contaminationouter volume signalphase encodingSingle-voxel MRS

Identifiers

PMID29755936
PMCPMC5942903

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.