Evidence map›Paper›PMID 29755826›Full record

ArticleKDD : proceedings. International Conference on Knowledge Discovery & Data Mining2017

Pharmacovigilance via Baseline Regularization with Large-Scale Longitudinal Observational Data.

Zhaobin Kuang, Peggy Peissig, Vítor Santos Costa, Richard Maclin, David Page

Abstract read
In one paragraph

Article in KDD : proceedings. International Conference on Knowledge Discovery & Data Mining, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Adverse Drug Reaction Discovery from Electronic Health Records with Deep Neural Networks.Proceedings of the ACM Conference on Health, Inference, and Learning · 2020
    Article
  2. Article
  3. Temporal Poisson Square Root Graphical Models.Proceedings of machine learning research · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhaobin KuangUniversity of Wisconsin-Madison.
Peggy PeissigMarshfield Clinic.
Vítor Santos CostaUniversidade do Porto.
Richard MaclinUniversity of Minnesota-Duluth.
David PageUniversity of Wisconsin-Madison.

Funding

TrainingU54AI117924 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI CRAVEN, MARK W. · 2014 to 2018
$11.3M
Machine Learning for Identifying Adverse Drug EventsR01GM097618 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI CALDWELL, MICHAEL DEFOIX, HANSEN, RICHARD A. · 2011 to 2018
$3.8M
NIAID NIH HHS U54 AI117924NIGMS NIH HHS R01 GM097618
6 · The paper itself

Abstract

Several prominent public health hazards [29] that occurred at the beginning of this century due to adverse drug events (ADEs) have raised international awareness of governments and industries about pharmacovigilance (PhV) [6,7], the science and activities to monitor and prevent adverse events caused by pharmaceutical products after they are introduced to the market. A major data source for PhV is large-scale longitudinal observational databases (LODs) [6] such as electronic health records (EHRs) and medical insurance claim databases. Inspired by the Self-Controlled Case Series (SCCS) model [27], arguably the leading method for ADE discovery from LODs, we propose baseline regularization, a regularized generalized linear model that leverages the diverse health profiles available in LODs across different

Indexed as

Adverse Drug Event DiscoveryBaseline RegularizationElectronic Health RecordsLongitudinal DataPharmacovigilance

Identifiers

PMID29755826
PMCPMC5945223

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.