Evidence map›Paper›PMID 29755771›Full record

ArticleJournal of gastrointestinal oncology2018

Preoperative survival calculator for resectable hepatocellular carcinoma.

Emmanuel Gabriel, Jin Kim, Katherine T Ostapoff, Kristopher Attwood, Sergei Kurenov, Boris Kuvshinoff, Steven N Hochwald, Steven J Nurkin

Open access · hybridAbstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Racial and Ethnic Disparities in Survival Among Patients With Hepatocellular Carcinoma in the United States: A Systematic Review and Meta-Analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emmanuel GabrielDepartment of Surgery, Section of Surgical Oncology, Mayo Clinic, Jacksonville, FL, USA.
Jin KimDepartment of Surgical Oncology, Roswell Park Cancer Institute Buffalo, Buffalo, NY, USA.
Katherine T OstapoffDepartment of Surgical Oncology, Roswell Park Cancer Institute Buffalo, Buffalo, NY, USA.
Kristopher AttwoodDepartment of Biostatistics, Roswell Park Cancer Institute Buffalo, Buffalo, NY, USA.
Sergei KurenovDepartment of Surgical Oncology, Roswell Park Cancer Institute Buffalo, Buffalo, NY, USA.
Boris KuvshinoffDepartment of Surgical Oncology, Roswell Park Cancer Institute Buffalo, Buffalo, NY, USA.
Steven N HochwaldDepartment of Surgical Oncology, Roswell Park Cancer Institute Buffalo, Buffalo, NY, USA.
Steven J NurkinDepartment of Surgical Oncology, Roswell Park Cancer Institute Buffalo, Buffalo, NY, USA.
Roswell Park Comprehensive Cancer Center · USMayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEstimation of preoperative overall survival (OS) of hepatocellular carcinoma (HCC) may guide surgical decision-making.

methodsOS was analyzed using the National Cancer Data Base from 1998-2012. Patients with HCC who underwent wedge resection, lobectomy or extended lobectomy were selected. Patients who had metastatic disease or previous treatment prior to surgery were excluded. Data was randomly allocated to model building (n

resultsHCC patients (n=5,455) who underwent curative resection had a median OS of 36 months (95% CI, 34-38 months) with 1- and 3-year OS of 73% (95% CI, 72-74%) and 50% (95% CI, 49-51%), respectively. The patient median age was 65, 66% of patients were male, median tumor size was 60 mm; clinical stage 1 =25%, stage 2 =30% and stage 3 =45%. Alpha fetoprotein (AFP) was elevated in 63% of patients. Factors significant in the prediction model included degree of resection, age, race, tumor size, grade, and histologic subtype.

conclusionsA preoperative OS calculator was developed to assist in the treatment evaluation and OS prediction of HCC patients.

Indexed as

Hepatocellular carcinoma (HCC)survival calculator

Identifiers

PMID29755771
PMCPMC5934157
OpenAlexW2783446006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.