Evidence map›Paper›PMID 29755683›Full record

ArticleOncotarget2018

Increased mucosal expression of miR-215 precedes the development of neoplasia in patients with long-standing ulcerative colitis.

Joel Pekow, Katherine Meckel, Urszula Dougherty, Haider I Haider, Zifeng Deng, John Hart, David T Rubin, Marc Bissonnette

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joel PekowSection of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, IL, USA.
Katherine MeckelSection of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, IL, USA.
Urszula DoughertySection of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, IL, USA.
Haider I HaiderSection of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, IL, USA.
Zifeng DengSection of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, IL, USA.
John HartSection of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, IL, USA.
David T RubinSection of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, IL, USA.
Marc BissonnetteSection of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, IL, USA.
University of Chicago · US

Funding

ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI ABADIE, VALERIE · 1990 to 2025
$29.8M
Novel microRNA regulatory networks predictive of colon carcinogenesis in IBDK08DK090152 · NIDDK · UNIVERSITY OF CHICAGO · PI PEKOW, JOEL · 2012 to 2016
$732k
NIDDK NIH HHS K08 DK090152NIDDK NIH HHS P30 DK042086
6 · The paper itself

Abstract

Identification of biological markers predicting the onset of neoplasia in patients with long-standing ulcerative colitis (UC) could allow for risk stratification in this population. In this study, we retrospectively identified subjects with chronic UC who developed colon neoplasia (

Indexed as

colon cancermiRNAneoplasiapredictive biomarkerulcerative colitis

Identifiers

PMID29755683
PMCPMC5945498
OpenAlexW2800946490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.