Evidence map›Paper›PMID 29755669›Full record

ArticleOncotarget2018

A stitch in time saves nine: external quality assessment rounds demonstrate improved quality of biomarker analysis in lung cancer.

Cleo Keppens, Véronique Tack, Nils 't Hart, Lien Tembuyser, Ales Ryska, Patrick Pauwels, Karen Zwaenepoel, Ed Schuuring, Florian Cabillic, Luigi Tornillo and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Lung cancer biomarker testing: perspective from Europe.Translational lung cancer research · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. A Root Cause Analysis Into the High Error Rate in Clinical Immunohistochemistry.Applied immunohistochemistry & molecular morphology : AIMM
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 6 countries.

Cleo KeppensUniversity of Leuven, Department of Public Health and Primary Care, Biomedical Quality Assurance Research Unit, Leuven, Belgium.
Véronique TackUniversity of Leuven, Department of Public Health and Primary Care, Biomedical Quality Assurance Research Unit, Leuven, Belgium.
Nils 't HartUniversity Medical Center Groningen, Department of Pathology, Groningen, The Netherlands.
Lien TembuyserUniversity of Leuven, Department of Public Health and Primary Care, Biomedical Quality Assurance Research Unit, Leuven, Belgium.
Ales RyskaCharles University Medical Faculty and University Hospital, Department of Pathology, Hradec Kralove, Czech Republic.
Patrick PauwelsCenter for Oncologic Research (CORE), University of Antwerp, Antwerp, Belgium.
Karen ZwaenepoelUniversity Hospital Antwerp, Department of Pathology, Edegem, Belgium.
Ed SchuuringUniversity Medical Center Groningen, Department of Pathology, Groningen, The Netherlands.
Florian CabillicCytogenetics and Cellular Biology Department, CHU de Rennes, Rennes, France.
Luigi TornilloUniversity of Basel, Basel, Switzerland.
Arne WarthUniversity Hospital Heidelberg, Heidelberg, Germany.
Wilko WeichertTechnical University Munich (TUM), Munich, Germany.
Elisabeth DequekerUniversity of Leuven, Department of Public Health and Primary Care, Biomedical Quality Assurance Research Unit, Leuven, Belgium.
EQA assessors expert group
University Medical Center Groningen · NLKU Leuven · BEUniversity of Antwerp · BECharles University · CZHeidelberg University · DEInserm · FRTechnical University of Munich · DEUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomarker analysis has become routine practice in the treatment of non-small cell lung cancer (NSCLC). To ensure high quality testing, participation to external quality assessment (EQA) schemes is essential. This article provides a longitudinal overview of the EQA performance for

Indexed as

biomarker analysisexternal quality assessmentmolecular pathologynon-small cell lung cancertargeted therapy

Identifiers

PMID29755669
PMCPMC5945546
OpenAlexW2801770572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.