ArticleChemosensory perception2018
Pilot Experiment: The Effect of Added Flavorants on the Taste and Pleasantness of Mixtures of Glycerol and Propylene Glycol.
Article in Chemosensory perception, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Device color influences e-cigarette flavor expectations, perception, and appeal.Chemical senses · 2026Article
- Effects of commercial unflavored and vanilla-flavored e-liquids on nicotine intake and withdrawal.bioRxiv : the preprint server for biology · 2026Article
- The ratio of propylene glycol to glycerol modulates nicotine taste and reward: more glycerol, more reward.Frontiers in pharmacology · 2026Article
- An integrated approach to smoky food flavor: Decoding key odorants, sensory contributions, and olfactory recognition mechanisms.Current research in food science · 2026Article
- Impact of vanilla flavor on nicotine taste, choice, intake, and seeking behaviors.Psychopharmacology · 2024Article
- Assessing toxicant emissions from e-liquids with DIY additives used in response to a potential flavour ban in e-cigarettes.Tobacco control · 2022Article
- Reinforcing effects of fentanyl and sufentanil aerosol puffs in rats.Psychopharmacology · 2022Article
- Animal Models to Investigate the Impact of Flavors on Nicotine Addiction and Dependence.Current neuropharmacology · 2022Review
- Chemosensory Contributions of E-Cigarette Additives on Nicotine Use.Frontiers in neuroscience · 2022Review
- Exposure to fruit-flavoring during adolescence increases nicotine consumption and promotes dose escalation.Neuropharmacology · 2021Article
- How Does the Use of Flavored Nicotine Vaping Products Relate to Progression Toward Quitting Smoking? Findings From the 2016 and 2018 ITC 4CV Surveys.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021Article
- History repeats itself: Role of characterizing flavors on nicotine use and abuse.Neuropharmacology · 2020Review
- Flavour types used by youth and adult tobacco users in wave 2 of the Population Assessment of Tobacco and Health (PATH) Study 2014-2015.Tobacco control · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
introductionThe US Food and Drug Administration banned most "sweet" flavorants for use in cigarettes due to the concern that sweet flavors appeal to young, beginning smokers. However, many of the same flavors, including fruity and confection-associated aromas (e.g. vanilla) are still used in e-cigarettes. Sweet flavors may have a number of effects, including enhancement of the taste of other ingredients. The current work focused on the impact of model flavorants on the taste of a mixture of propylene glycol and vegetable glycerine, solvents used in most e-cigarettes and related products.
methodsA device delivered mixtures of propylene glycol and vegetable glycerine into the mouth in parallel with puffs of clean air (control) or odorized air. Aromas included two "fruity" esters ("pineapple" and "banana"), two confection-associated aromas ("vanilla" and "caramel/malty"), menthol (not a "sweet" aroma, but commonly used in e-cigarettes), and a "burnt" aroma not expected enhance flavor. Twenty young adults, aged 18-25, rated the sweetness, bitterness, and pleasantness of all stimuli (within-subjects design).
resultsBoth fruity aromas significantly enhanced sweetness, both confection-associated aromas significantly enhanced pleasantness, and the caramel/malty aroma significantly reduced bitterness. Menthol and the "burnt" aroma had no measurable effects on the taste of solvent mixtures.
conclusionSome flavorants modulated the taste of solvents commonly used in e-cigarettes in ways consistent with an enhanced sensory profile. IMPLICATIONS: If similar effects occur in actual products, improved flavor profiles could facilitate continued use, particularly in non-smokers experimenting with e-cigarettes and related products.
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