ReviewThe Japanese dental science review2018
Histological and immunological characteristics of the junctional epithelium.
Review in The Japanese dental science review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Crude Plant Extracts and Their Anti-Inflammatory Potential in Oral Inflammatory Cell Models: A Systematic Review of In Vitro Studies.International journal of molecular sciences · 2025Pooled it
- Intraepithelial lymphocytes in human oral diseases.Frontiers in immunology · 2025Pooled it
- Gingival Response to Dental Implant: Comparison Study on the Effects of New Nanopored Laser-Treated vs. Traditional Healing Abutments.International journal of molecular sciences · 2020Trial
- Fluorapatite-Coated Percutaneous Osseointegrated Prostheses Limit Epidermal Downgrowth and Promote Periprosthetic Healing in a Weight-Bearing Sheep Model-A Preliminary Study.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Article
- Histopathological Features and Clinical Findings of Feline Chronic Gingivostomatitis (FCGS) in Cats (Veterinary medicine international · 2026Article
- Article
- The Morphogenesis, Pathogenesis, and Molecular Regulation of Human Tooth Development-A Histological Review.International journal of molecular sciences · 2025Review
- Localizations of Laminin Chains Suggest Their Multifaceted Functions in Mouse Tooth Development.International journal of molecular sciences · 2025Article
- Mapping Small Extracellular Vesicle Secretion Potential in Healthy Human Gingiva Using Spatial Transcriptomics.Current issues in molecular biology · 2025Article
- Bridging the Gap: Soft Tissue Considerations in Dental Implants From Microscopic to Macroscopic Levels.Cureus · 2024Review
- Single-cell and spatially resolved interactomics of tooth-associated keratinocytes in periodontitis.Nature communications · 2024Article
- Article
- A Review of a Breakdown in the Barrier: Tight Junction Dysfunction in Dental Diseases.Clinical, cosmetic and investigational dentistry · 2024Review
- Three-Dimensional Humanized Model of the Periodontal Gingival Pocket to Study Oral Microbiome.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Role of junctional epithelium in maintaining dento-gingival adhesion and periodontal health.Frontiers in dental medicine · 2023Review
- Junctional epithelium and hemidesmosomes: Tape and rivets for solving the "percutaneous device dilemma" in dental and other permanent implants.Bioactive materials · 2022Review
- Epithelial cell attachment and adhesion protein expression on novel in sol TiOJournal of biomedical materials research. Part B, Applied biomaterials · 2022Article
- Review
- Diverse stem cells for periodontal tissue formation and regeneration.Genesis (New York, N.Y. : 2000) · 2022Review
- A Novel Alveolar Distractor Incorporating Nickel-Titanium Alloy Springs: A Preliminary In Vitro Study.Materials (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The continuity of epithelial tissue is collapsed by tooth eruption. The junctional epithelium (JE) is attached to the tooth surface by hemidesmosomes, which constitutes the front-line defense against periodontal bacterial infection. JE constitutively expresses intercellular adhesion molecule-1 (ICAM-1), and neutrophils and lymphocytes penetrate into JE via interaction between ICAM-1 and LFA-1 expressed on the surface of these migrating cells. JE also expresses cytokines and chemokines. These functions of JE are maintained even in germ-free condition. Therefore, the constitutive expression of adhesion molecules, cytokines, and chemokines might be used not only for anti-pathogenic defense but also for maintaining the physiological homeostasis of JE. In this review, we have mainly focused on the structural and functional features of JE, and discussed the function of intraepithelial lymphocytes in JE as a front-line anti-microbial defense barrier and regulator of JE hemostasis.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.