ArticleBehavioural neurology2018
Morphological Biomarker Differentiating MCI Converters from Nonconverters: Longitudinal Evidence Based on Hemispheric Asymmetry.
Article in Behavioural neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Structural brain improvements following individually tailored serious exergame-based training in mild neurocognitive disorders: exploratory randomized controlled trial.Alzheimer's research & therapy · 2025Trial
- Variations of global brain asymmetry are associated with aging and related diseases.Science advances · 2026Article
- Selective vulnerability of hippocampal sub-regions in patients with subcortical vascular mild cognitive impairment.Brain imaging and behavior · 2024Article
- Estimating individual trajectories of structural and cognitive decline in mild cognitive impairment for early prediction of progression to dementia of the Alzheimer's type.Scientific reports · 2024Article
- Characterization of Cognitive Function in Survivors of Diffuse Gliomas Using Morphometric Correlation Networks.Tomography (Ann Arbor, Mich.) · 2022Article
- Structural Alteration of Medial Temporal Lobe Subfield in the Amnestic Mild Cognitive Impairment Stage of Alzheimer's Disease.Neural plasticity · 2022Article
- Individual prediction of hemispheric similarity of functional connectivity during normal aging.Frontiers in psychiatry · 2022Article
- Effects of Meditation on Structural Changes of the Brain in Patients With Mild Cognitive Impairment or Alzheimer's Disease Dementia.Frontiers in human neuroscience · 2021Article
- Grey Matter Loss at Different Stages of Cognitive Decline: A Role for the Thalamus in Developing Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2021Article
- Changes in Gray Matter Asymmetries of the Fusiform and Parahippocampal Gyruses in Patients With Subcortical Ischemic Vascular Disease.Frontiers in neurology · 2020Article
- Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation.Brain : a journal of neurology · 2019Article
- Differential Associations Between Volumes of Atrophic Cortical Brain Regions and Memory Performances in Early and Late Mild Cognitive Impairment.Frontiers in aging neuroscience · 2019Article
- Multiplex Networks for Early Diagnosis of Alzheimer's Disease.Frontiers in aging neuroscience · 2018Article
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3 authors.
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Abstract
Identifying subjects with mild cognitive impairment (MCI) who may probably progress to Alzheimer's disease (AD) is important for better understanding the disease mechanisms and facilitating early treatments. In addition to the direct volumetric and thickness measurement based on high-resolution magnetic resonance imaging (MRI), hemispheric asymmetry could be a potential index to detect morphological variations in MCI patients with a high risk of conversion to AD. The present study collected a set of longitudinal MRI data from 53 MCI converters and nonconverters and investigated the asymmetry differences between groups. Asymmetry variation was observed in the medial temporal lobe, especially in the entorhinal cortex, between converters and nonconverters 3 years before the former developed AD. The proposed asymmetry analysis was observed to be sensitive to detect morphological changes between groups as compared to the methods of voxel-based morphometry (VBM) and thickness measurement. Hemispheric asymmetry in specific brain regions as a neuroimaging biomarker can provide helpful information for prediction of MCI conversion.
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