ReviewInternational journal of endocrinology2018
Cataract as Early Ocular Complication in Children and Adolescents with Type 1 Diabetes Mellitus.
Review in International journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- ISPAD Clinical Practice Consensus Guidelines 2018: Microvascular and macrovascular complications in children and adolescents.Pediatric diabetes · 2018Guideline
- Etiologic Spectrum and Surgical Epidemiology of Pediatric Cataracts in Kazakhstan: A Three-Year Retrospective Study from Two Tertiary Eye-Care Centers.Medicina (Kaunas, Lithuania) · 2026Article
- Cataracts as the presenting symptom of type 1 diabetes mellitus.JCEM case reports · 2026Article
- Observational
- New-onset Type 1 Diabetes Mellitus Presenting as Bilateral Cataracts in a 15-year-old Girl.JCEM case reports · 2025Article
- Association between age at diagnosis of diabetes and ocular disease: Insights from a recent article.World journal of diabetes · 2025Article
- Type 1 Diabetes and Cataracts: Investigating Mediating Effects of Serum Metabolites Using Bidirectional Mendelian Randomization.Metabolites · 2024Article
- Prevalence and Predictors of Diabetic Retinopathy, Its Progression and Regression in Indian Children and Youth With Type-1 Diabetes.Clinical medicine insights. Endocrinology and diabetes · 2024Article
- LncRNA GAS5 regulates migration and epithelial-to-mesenchymal transition in lens epithelial cells via the miR-204-3p/TGFBR1 axis.Laboratory investigation; a journal of technical methods and pathology · 2022Article
- Resveratrol protects against high glucose-induced oxidative damage in human lens epithelial cells by activating autophagy.Experimental and therapeutic medicine · 2021Article
- Epidemiology of Ocular Manifestations in Autoimmune Disease.Frontiers in immunology · 2021Review
- Effect of thioltransferase on oxidative stress induced by high glucose and advanced glycation end products in human lens epithelial cells.International journal of ophthalmology · 2021Article
- Chrysin Reduces Oxidative Stress but Does Not Affect Polyol Pathway in the Lenses of Type 1 Diabetic Rats.Antioxidants (Basel, Switzerland) · 2020Article
- High Risk of Early Cataracts in Young Type 1 Diabetes Group: A Nationwide Cohort Study.International journal of endocrinology · 2020Article
- Cataract in diabetes mellitus.World journal of diabetes · 2019Review
- Diabetes cataract in a 10-year-old girl with new-onset type 1 diabetes mellitus.BMJ case reports · 2019Article
- High glucose: activating autophagy and affecting the biological behavior of human lens epithelial cells.International journal of ophthalmology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cataract is a rare manifestation of ocular complication at an early phase of T1DM in the pediatric population. The pathophysiological mechanism of early diabetic cataract has not been fully understood; however, there are many theories about the possible etiology including osmotic damage, polyol pathway, and oxidative stress. The prevalence of early diabetic cataract in the population varies between 0.7 and 3.4% of children and adolescents with T1DM. The occurrence of diabetic cataract in most pediatric patients is the first sign of T1DM or occurs within 6 months of diagnosis of T1DM. Today, there are many experimental therapies for the treatment of diabetic cataract, but cataract surgery continues to be a gold standard in the treatment of diabetic cataract. Since the cataract is the leading cause of visual impairment in patients with T1DM, diabetic cataract requires an initial screening as well as continuous surveillance as a measure of prevention and this should be included in the guidelines of pediatric diabetes societies.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.