ArticleFrontiers in genetics2018
Genome-Wide Association Analysis of Age-Dependent Egg Weights in Chickens.
Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Evolution under the city's shadow: reproductive divergence of urban and rural great tits revealed by a common garden experiment.Evolution letters · 2026Article
- Genome-Wide Association Studies Reveal Key Candidate Genes for Egg Weight and Quality Components in an FVeterinary sciences · 2026Article
- PGS-GS: a framework integrating polygenic scores and genomic selection in animal breeding.Briefings in bioinformatics · 2026Article
- Stochastic simulations to optimize genomic selection for laying hens: Impact of generation interval and genotyping in the context of extended laying period.Poultry science · 2026Article
- Bayesian fine-mapping pinpoints candidate genes and pleiotropic loci of production traits from a chicken backcrossing scheme.BMC genomics · 2026Article
- Gsformer: a dual-architecture deep learning framework with CNN-self-attention and sparse-attention for genomic selection.Genetics, selection, evolution : GSE · 2026Article
- Normalized cumulative gain as an alternative evaluation measure for genomic selection models.Genetics, selection, evolution : GSE · 2025Article
- Identification of candidate genes affecting egg weight trait of Putian Black duck based on whole genome resequencing.Animal biotechnology · 2025Article
- Genome-Wide Egg Hunt: Unhiding Candidate Genes for Egg Component Traits in Layers of an FAnimals : an open access journal from MDPI · 2025Article
- Integrative multi-omics analysis deciphers the regulatory mechanisms of egg weight traits in chickens.Poultry science · 2025Article
- A 17.1 kb duplication downstream GATA6 is strongly associated with egg weight in chicken.BMC genomics · 2025Article
- ExAutoGP: Enhancing Genomic Prediction Stability and Interpretability with Automated Machine Learning and SHAP.Animals : an open access journal from MDPI · 2025Article
- Mutual information-based best linear unbiased prediction for enhanced genomic prediction accuracy.Journal of animal science · 2025Article
- High-value valorization ofFrontiers in veterinary science · 2025Article
- Genome-wide association studies of egg production traits by whole genome sequencing of Laiwu Black chicken.Poultry science · 2024Article
- Article
- Genetic parameters, reciprocal cross differences, and age-related heterosis of egg-laying performance in chickens.Genetics, selection, evolution : GSE · 2023Article
- Association analysis of production traits of Japanese quail (Coturnix japonica) using restriction-site associated DNA sequencing.Scientific reports · 2023Article
- Genome-Wide Association Study of Egg Production Traits in Shuanglian Chickens Using Whole Genome Sequencing.Genes · 2023Article
- Exploring the potential of incremental feature selection to improve genomic prediction accuracy.Genetics, selection, evolution : GSE · 2023Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Egg weight (EW) is an economically-important trait and displays a consecutive increase with the hen's age. Because extremely large eggs cause a range of problems in the poultry industry, we performed a genome-wide association study (GWAS) in order to identify genomic variations that are associated with EW. We utilized the Affymetrix 600 K high density SNP array in a population of 1,078 hens at seven time points from day at first egg to 80 weeks age (EW80). Results reveal that a 90 Kb genomic region (169.42 Mb ~ 169.51 Mb) in GGA1 is significantly associated with EW36 and is also potentially associated with egg weight at 28, 56, and 66 week of age. The leading SNP could account for 3.66% of the phenotypic variation, while two promising genes (DLEU7 and MIR15A) can be mapped to this narrow significant region and may affect EW in a pleiotropic manner. In addition, one gene (CECR2 on GGA1) and two genes (MEIS1 and SPRED2 on GGA3), which involved in the processes of embryogenesis and organogenesis, were also considered to be candidates related to first egg weight (FEW) and EW56, respectively. Findings in our study could provide worthy theoretical basis to generate eggs of ideal size based on marker assisted breeding selection.
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