Evidence map›Paper›PMID 29755473›Full record

ArticleFrontiers in immunology2018

Differential Effect of Viable Versus Necrotic Neutrophils on

David M Lowe, Julie Demaret, Nonzwakazi Bangani, Justine K Nakiwala, Rene Goliath, Katalin A Wilkinson, Robert J Wilkinson, Adrian R Martineau

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 48 citations in OpenAlex.

  1. Ly6GeLife · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Neutrophils inVaccines · 2023
    Review
  7. The roles of neutrophils in non-tuberculous mycobacterial pulmonary disease.Annals of clinical microbiology and antimicrobials · 2023
    Review
  8. Exploring the Role of Low-Density Neutrophils DuringFrontiers in cellular and infection microbiology · 2022
    Review
  9. The Role of Gut and Lung Microbiota in Susceptibility to Tuberculosis.International journal of environmental research and public health · 2021
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Host defense mechanisms against Mycobacterium tuberculosis.Cellular and molecular life sciences : CMLS · 2020
    Review
  17. Article
  18. Article
  19. Article
  20. Immune Response toFrontiers in pediatrics · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

David M LoweWellcome Centre for Infectious Diseases Research in Africa, Department of Medicine, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Julie DemaretBarts and The London School of Medicine, Blizard Institute, Queen Mary University of London, London, United Kingdom.
Nonzwakazi BanganiWellcome Centre for Infectious Diseases Research in Africa, Department of Medicine, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Justine K NakiwalaWellcome Centre for Infectious Diseases Research in Africa, Department of Medicine, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Rene GoliathWellcome Centre for Infectious Diseases Research in Africa, Department of Medicine, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Katalin A WilkinsonWellcome Centre for Infectious Diseases Research in Africa, Department of Medicine, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Robert J WilkinsonWellcome Centre for Infectious Diseases Research in Africa, Department of Medicine, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Adrian R MartineauBarts and The London School of Medicine, Blizard Institute, Queen Mary University of London, London, United Kingdom.
Wellcome Centre for Infectious Diseases Research in Africa · ZAQueen Mary University of London · GBUniversity of Cape Town · ZAUniversity of Antwerp · BE

Funding

Cancer Research UK FC00110218Medical Research Council FC00110218Medical Research Council MC_U117588499Wellcome Trust 087754Wellcome Trust 097684Wellcome Trust 104803Wellcome Trust 203135Wellcome Trust FC00110218
6 · The paper itself

Abstract

Neutrophils exert both positive and negative influences on the host response to tuberculosis, but the mechanisms by which these differential effects are mediated are unknown. We studied the impact of live and dead neutrophils on the control of

Indexed as

Biological AssayCytokinesHost-Pathogen InteractionsHumansMycobacterium tuberculosisNecrosisNeutrophilsTuberculosisCytokinesmycobacterianecrosisneutrophiltuberculosisviability

Identifiers

PMID29755473
PMCPMC5934482
OpenAlexW2800394003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.