ArticleFrontiers in neurology2018
Leg Prosthesis With Somatosensory Feedback Reduces Phantom Limb Pain and Increases Functionality.
Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05807607 (Peripheral Nerve and Spinal Cord Stimulation in Patients With Pain Syndrome as a Result of Lower Limb Amputation in Order to Relieve Pain Syndrome and Develop Phantom Pain Biomarkers), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Peripheral Nerve and Spinal Cord Stimulation in Patients With Pain Syndrome as a Result of Lower Limb Amputation in Order to Relieve Pain Syndrome and Develop Phantom Pain Biomarkers
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- A review of user needs to drive the development of lower limb prostheses.Journal of neuroengineering and rehabilitation · 2022Pooled it
- Biofeedback Systems for Gait Rehabilitation of Individuals with Lower-Limb Amputation: A Systematic Review.Sensors (Basel, Switzerland) · 2020Pooled it
- The prevalence and risk factors for phantom limb pain in people with amputations: A systematic review and meta-analysis.PloS one · 2020Pooled it
- Perceptual Design and Evaluation of a Forearm-Based Vibrotactile Interface for Transfemoral Prosthetic Feedback.Biomimetics (Basel, Switzerland) · 2026Article
- Phantom limb telescoping in individuals with limb loss: links to anxiety, depression, and pain-related measures.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Development and assessment of vibrotactile feedback from the embedded sensors of a microprocessor-controlled knee prosthesis.Journal of neuroengineering and rehabilitation · 2025Article
- Vibration, temperature, and humidity influence the perception of electrocutaneous stimulation for occupational warning.Scientific reports · 2025Article
- Ultra-conformable tattoo electrodes for providing sensory feedback via transcutaneous electrical nerve stimulation.Scientific reports · 2025Article
- Compensation for balance disorders: analysis of this multifactorial process.European journal of translational myology · 2025Article
- Haptic Feedback Systems for Lower-Limb Prosthetic Applications: A Review of System Design, User Experience, and Clinical Insights.Bioengineering (Basel, Switzerland) · 2025Review
- The German adaptation of the Amputee Body Image Scale and the importance of psychosocial adjustment to prosthesis use.Scientific reports · 2025Article
- Somatosensory restoration and neural control strategies in lower-limb prostheses.npj biomedical innovations · 2025Review
- Sensory feedback for gait in transtibial amputees: a narrative review of technologies and clinical outcomes.Frontiers in bioengineering and biotechnology · 2025Review
- Pain After Lower Limb Amputations: Insights from the Heidelberg Amputation Registry.Medicina (Kaunas, Lithuania) · 2024Article
- Clinical Applications and Future Translation of Somatosensory Neuroprostheses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- [Fillet flap transfer as alternative to conventional lower limb amputation].Unfallchirurgie (Heidelberg, Germany) · 2024Review
- Physiotherapy: A potential and novel treatment approach for phantom limb pain in post-amputee patients - A systematic review.British journal of pain · 2024Article
- Epidemiology and risk factors for phantom limb pain.Frontiers in pain research (Lausanne, Switzerland) · 2024Review
- Design dimensions of electrocutaneous warning stimulation patterns in workplace safety devices.PloS one · 2024Article
- Pain and Reorganization after Amputation: Is Interoceptive Prediction a Key?The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phantom limb pain (PLP) develops in most patients with lower limb amputation. Changes in the peripheral and central nervous system (CNS) are hypothesized to contribute to PLP. Based on ideas to modify neural reorganization within the CNS, the aim of the study was to test, whether prostheses with somatosensory feedback might help to reduce PLP, and increase the functionality of movement with a prosthesis. We therefore equipped the prostheses of 14 lower leg amputees with a simple to use feedback system that provides electrocutaneous feedback to patients' thigh whenever the foot and toes of the prosthesis touch the ground. Two weeks of training with such a feedback prosthesis reduced PLP, increased the functional use of the prosthesis, and increased patients' satisfaction with prosthesis use. We found a significant overall reduction of PLP during the course of the training period. Most patients reported lower PLP intensities at the end of the day while before training they have usually experienced maximal PLP intensities. Furthermore, patients also reported larger walking distances and more stable walking and better posture control while walking on and across a bumpy or soft ground. After training, the majority of participants (9/14) preferred such a feedback system over no feedback. This study extends former observations of a similar training procedure with arm amputees who used a similar feedback training to improve the functionality of an arm prosthesis in manipulating and grasping objects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.