Trial reportThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2018
Dynamic thiol/disulphide homeostasis in acute pancreatitis.
Trial report in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 26 citations in OpenAlex.
- Altered blood parameters in "major depression" patients receiving repetitive transcranial magnetic stimulation (rTMS) therapy: a randomized case-control study.Translational psychiatry · 2024Trial
- The effect of low flow anesthesia with sevoflurane on oxidative status: A prospective, randomized study.Saudi medical journal · 2022Trial
- The ameliorative effects of hesperidin in rats developed hepatotoxicity with deltamethrin.Iranian journal of basic medical sciences · 2025Article
- Dynamic thiol/disulfide homeostasis as oxidative stress marker in diabetic ketoacidosisTurkish journal of medical sciences · 2021Article
- The effect of laparoscopic and open surgery on oxidative DNA damage and IL-37 in children with acute appendicitis.Irish journal of medical science · 2021Article
- Article
- Thiol-disulfide homeostasis: an integrated approach with biochemical and clinical aspectsTurkish journal of medical sciences · 2020Review
- Thiol/disulfide homeostasis and ischemia modified albumin levels in autoimmune gastritis and their relations with gastric emptyingTurkish journal of medical sciences · 2020Article
- Impaired thiol/disulfide homeostasis in patients with mild acute pancreatitis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsThe dynamic thiol/disulfide homeostasis plays pivotal roles in many physiological mechanisms in an organism. We aimed to investigate whether dynamic thiol/disulfide homeostasis changes among patients with acute pancreatitis. MATERIALS AND
methodsThis prospective trial contained 45 patients with acute pancreatitis and 45 sex-and age-matched healthy volunteers as control group. Thiol/disulfide homeostasis parameters were measured by a novel and automated assay, and detected results were compared between the two groups.
resultsDisulfide/total thiol percent ratio and disulfide/native thiol percent ratios were significantly higher in acute pancreatitis group; besides the native thiol, total thiol levels and native thiol/total thiol percent ratios were significantly lower (for all p < 0.001).
conclusionThe thiol/disulfide homeostasis is impaired in acute pancreatitis with a shift toward the oxidative status, and this deficiency might be a pathogenic factor in acute pancreatitis. The correction of this thiol/disulfide imbalance may be a new target in the management of acute pancreatitis.
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Registered trials
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