Evidence map›Paper›PMID 29754868›Full record

ArticleThe Journal of pediatrics2018

Attitudes Surrounding the Management of Neonates with Severe Necrotizing Enterocolitis.

Gillian C Pet, Ryan M McAdams, Lilah Melzer, Assaf P Oron, Simon P Horslen, Adam Goldin, Patrick J Javid

Open access · greenAbstract read
In one paragraph

Article in The Journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Guideline
  2. Is Necrotizing Enterocolitis Totalis a Distinct Disease Process?Pediatric gastroenterology, hepatology & nutrition · 2026
    Article
  3. Necrotizing enterocolitis.Nature reviews. Disease primers · 2026
    Review
  4. Article
  5. Article
  6. Current operative approaches for necrotizing enterocolitis.World journal of pediatric surgery · 2026
    Review
  7. Context factors in clinical decision-making: a scoping review.BMC medical informatics and decision making · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Multidisciplinary Management in Pediatric Ultrashort Bowel Syndrome.Journal of multidisciplinary healthcare · 2020
    Review
  12. Short Bowel Syndrome.Current treatment options in pediatrics · 2019
    Article
  13. Variable management strategies for NEC totalis: a national survey.Journal of perinatology : official journal of the California Perinatal Association · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gillian C PetDivision of Neonatology, Johns Hopkins Hospital, Baltimore, MD. Electronic address: gilliancpet@gmail.com.
Ryan M McAdamsDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Lilah MelzerDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA.
Assaf P OronChildren's Core for Biomedical Sciences, Seattle Children's Research Institute, Seattle, WA.
Simon P HorslenDivision of Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA.
Adam GoldinDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA.
Patrick J JavidDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA.
Seattle Children's Hospital · USJohns Hopkins Hospital · USUniversity of Wisconsin–Madison · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
NCATS NIH HHS UL1 TR002319
6 · The paper itself

Abstract

objectivesTo assess providers' recommendations as to comfort care versus medical and surgical management in clinical scenarios of newborns with severe bowel loss and to assess how a variety of factors influence providers' decision making. STUDY

designWe conducted a survey of pediatric surgeons and neonatologists via the American Pediatric Surgical Association and American Academy of Pediatrics Section of Neonatal-Perinatal Medicine. We examined how respondents' recommendations were affected by a variety of patient and provider factors.

resultsThere were 288 neonatologists and 316 pediatric surgeons who responded. Irrespective of remaining bowel length, comfort care was recommended by 73% of providers for a premature infant with necrotizing enterocolitis and 54% for a full-term infant with midgut volvulus. The presence of comorbidities and earlier gestational age increased the proportion of providers recommending comfort care. Neonatologists were more likely to recommend comfort care than surgeons across all scenarios (OR, 1.45-2.00; P < .05), and this difference was more pronounced with infants born closer to term. In making these recommendations, neonatologists placed more importance on neurodevelopmental outcomes (P < .001), and surgeons emphasized experience with long-term quality of life (P < .001).

conclusionDespite a contemporary survival of >90% in infants with intestinal failure, a majority of providers still recommend comfort care in infants with massive bowel loss. Significant differences were identified in clinical decision making between surgeons and neonatologists. These data reinforce the need for targeted education on long-term outcomes in intestinal failure to neonatal and surgical providers.

Indexed as

Attitude of Health PersonnelDigestive System Surgical ProceduresPalliative CareClinical Decision-MakingEnterocolitis, NecrotizingHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesLogistic ModelsNeonatologistsPrognosisQuality of LifeSeverity of Illness IndexSurgeonsSurveys and Questionnairesintestinal failurepremature infant

Identifiers

PMID29754868
PMCPMC6063789
OpenAlexW2800711093

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.