Evidence map›Paper›PMID 29754863›Full record

ArticleThe Journal of pediatrics2018

Relationships of Anxiety and Depression with Cardiovascular Health in Youth with Normal Weight to Severe Obesity.

Amy C Gross, Alexander M Kaizer, Justin R Ryder, Claudia K Fox, Kyle D Rudser, Donald R Dengel, Aaron S Kelly

Abstract readMulticenter Study
In one paragraph

Article in The Journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Gender Differences in the Association Between Depression, Anxiety and Cardiovascular Mortality in Hypertensive Patients: A Cohort Study.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Blood pressure response to noise in children and adolescents.Journal of clinical hypertension (Greenwich, Conn.) · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amy C GrossDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN; Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN. Electronic address: acgross@umn.edu.
Alexander M KaizerDivision of Biostatistics, University of Minnesota School of Public Health, Minneapolis, MN.
Justin R RyderDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN; Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN.
Claudia K FoxDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN; Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN.
Kyle D RudserCenter for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN; Division of Biostatistics, University of Minnesota School of Public Health, Minneapolis, MN.
Donald R DengelDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN; Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN; School of Kinesiology, University of Minnesota, Minneapolis, MN.
Aaron S KellyDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN; Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN; Department of Medicine, University of Minnesota Medical School, Minneapolis, MN.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Obesity and Energy Metabolism CoreP30DK050456 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BERNLOHR, DAVID A · 1995 to 2015
$17.0M
Validation of Circulating Endothelial Cells and Microparticles in YouthR01HL110957 · NHLBI · UNIVERSITY OF MINNESOTA · PI KELLY, AARON S · 2012 to 2016
$3.2M
NCATS NIH HHS UL1 TR000114NHLBI NIH HHS R01 HL110957NIDDK NIH HHS P30 DK050456
6 · The paper itself

Abstract

objectiveTo evaluate the relationships of depression and anxiety symptoms with cardiovascular disease (CVD) risk factors and measures of vascular health in youth. STUDY

designParticipants (n = 202) were 8- to 18-year-olds from a cross-sectional study evaluating cardiovascular health across a wide range of body mass index values (normal weight to severe obesity). CVD risk measurement included blood pressure, fasting lipids, glucose, insulin, carotid artery intima-media thickness, compliance and distensibility, brachial artery flow-mediated dilation, carotid-radial artery pulse wave velocity, body fat percentage, and a metabolic syndrome cluster score. Anxiety and depression symptoms were self-reported on the Screen for Child Anxiety Related Disorders and Center for Epidemiological Studies Depression Scale for Children. Two sets of adjustment variables were used in evaluation of differences between those with and without anxiety or depression symptomatology for the CVD risk factor and vascular outcomes. The first set included adjustment for Tanner stage, sex, and race; the second was additionally adjusted for percent body fat.

resultsAnxiety was not significantly associated with CVD risk factors or vascular health in either model. Depression was associated with high-density lipoprotein cholesterol, triglycerides, and metabolic syndrome cluster score; these relationships were attenuated when accounting for percent body fat.

conclusionsWhen accounting for body fat, we found no clear relationship of self-reported depression or anxiety symptoms with CVD risk factors or vascular health in youth.

Indexed as

Body WeightMental HealthAdolescentAnxietyCardiovascular DiseasesChildCross-Sectional StudiesDepressionFemaleHumansIncidenceMalePediatric ObesityPrognosisRisk FactorsUnited Statescardiovascular diseasemental healthpediatrics

Identifiers

PMID29754863
PMCPMC6063783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.