Evidence map›Paper›PMID 29754699›Full record

SynthesisVaccine2018

Systematic review of the incremental costs of interventions that increase immunization coverage.

Sachiko Ozawa, Tatenda T Yemeke, Kimberly M Thompson

Abstract readSystematic Review
In one paragraph

Synthesis in Vaccine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  19. An Updated Economic Analysis of the Global Polio Eradication Initiative.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Article
  20. Health and Economic Outcomes Associated with Polio Vaccine Policy Options: 2019-2029.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sachiko OzawaDivision of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA; Department of Maternal and Child Health, UNC Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. Electronic address: ozawa@unc.edu.
Tatenda T YemekeDivision of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA.
Kimberly M ThompsonKid Risk, Inc., Columbus, OH, USA.

Funding

CGH CDC HHS U2R GH001913
6 · The paper itself

Abstract

Achieving and maintaining high vaccination coverage requires investments, but the costs and effectiveness of interventions to increase coverage remain poorly characterized. We conducted a systematic review of the literature to identify peer-reviewed studies published in English that reported interventions aimed at increasing immunization coverage and the associated costs and effectiveness of the interventions. We found limited information in the literature, with many studies reporting effectiveness estimates, but not providing cost information. Using the available data, we developed a cost function to support future programmatic decisions about investments in interventions to increase immunization coverage for relatively low and high-income countries. The cost function estimates the non-vaccine cost per dose of interventions to increase absolute immunization coverage by one percent, through either campaigns or routine immunization. The cost per dose per percent increase in absolute coverage increased with higher baseline coverage, demonstrating increasing incremental costs required to reach higher coverage levels. Future studies should evaluate the performance of the cost function and add to the database of available evidence to better characterize heterogeneity in costs and generalizability of the cost function.

Indexed as

Models, StatisticalBacterial InfectionsBacterial VaccinesCost-Benefit AnalysisDeveloped CountriesDeveloping CountriesHealth Care CostsHumansImmunization ProgramsIncomeVaccinationVaccination CoverageViral VaccinesVirus DiseasesBacterial VaccinesViral VaccinesCostEffectivenessInterventionReviewVaccination

Identifiers

PMID29754699
PMCPMC7853081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.