Evidence map›Paper›PMID 29754327›Full record

SynthesisRheumatology international2018

The many faces of IgG4-related disease: report of a case with inaugural recurrent aortic aneurism ruptures and literature review.

Mariana Luís, Luísa Brites, Bruno Fernandes, Diogo Jesus, Tânia Santiago, Sara Serra, João Rovisco, Lina Carvalho, José António P da Silva, Armando Malcata

Abstract readCase ReportsSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Rheumatology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mariana LuísRheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal. maryanaluys@gmail.com.ORCID 0000-0001-9581-7088
Luísa BritesRheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0002-0234-4902
Bruno FernandesAnatomical Pathology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0002-2446-0007
Diogo JesusRheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0003-3136-0722
Tânia SantiagoRheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0002-1562-4022
Sara SerraRheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
João RoviscoRheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0002-2695-5257
Lina CarvalhoAnatomical Pathology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0001-8349-4488
José António P da SilvaRheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0002-2782-6780
Armando MalcataRheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Hospitais da Universidade de Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular involvement in IgG4-related disease (IgG4-RD), is a well-recognized feature and large vessel commitment, especially the aorta, can be the only manifestation of the disease. Being a newly recognized disease, its diagnosis and workup still represents a challenge in clinical practice. A 47-year-old-man with two aortic aneurysms ruptures, one at abdominal and the other at thoracic level, was referred to our rheumatology department. The initial analysis of the surgical specimen obtained 3 years earlier revealed a nonspecific aortitis. Re-evaluation of the biopsy with immunohistology now demonstrated the presence of IgG4 deposits. Evidence-based recommendations regarding diagnosis, treatment and follow-up of IgG4-related large-vessel involvement are lacking. In this particular case, histopathology were crucial. The authors review and discuss vascular involvement in IgG4-RD and respective treatment options.

Indexed as

AgedAortic Aneurysm, AbdominalAortic Aneurysm, ThoracicAortic RuptureAortitisBiomarkersFemaleHumansImmunoglobulin G4-Related DiseaseImmunologic FactorsMaleMiddle AgedPlasma CellsRituximabBiomarkersImmunologic FactorsRituximabAortitisIgG4 related-diseaseLarge-vessel diseaseTreatment

Identifiers

PMID29754327
OpenAlexW2799894235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.