ArticleBiophysical reviews2018
Controlling the mechanoelasticity of model biomembranes with room-temperature ionic liquids.
Article in Biophysical reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Lipid Saturation and Cholesterol Drive the Mechanical Response of Lipid Bilayer to Ionic Liquid: An Atomic Force Microscopy Study.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Ionic liquids meet lipid bilayers: a state-of-the-art review.Biophysical reviews · 2023Review
- Absorption of the [bmim][Cl] Ionic Liquid in DMPC Lipid Bilayers across Their Gel, Ripple, and Fluid Phases.The journal of physical chemistry. B · 2022Article
- Mechanisms of action of ionic liquids on living cells: the state of the art.Biophysical reviews · 2020Review
- From protein and its hydration water dynamics to controlling mechano-elasticity of cellular lipid membranes and cell migration via ionic liquids.Biophysical reviews · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Room-temperature ionic liquids (RTILs) are a vast class of organic non-aqueous electrolytes whose interaction with biomolecules is receiving great attention for potential applications in bio-nano-technology. Recently, it has been shown that RTILs dispersed at low concentrations at the water-biomembrane interface diffuse into the lipid region of the biomembrane, without disrupting the integrity of the bilayer structure. In this letter, we present the first exploratory study on the effect of absorbed RTILs on the mechanoelasticity of a model biomembrane. Using atomic force microscopy, we found that both the rupture force and the elastic modulus increase upon the insertion of RTILs into the biomembrane. This preliminary result points to the potential use of RTILs to control the mechanoelasticity of cell membranes, opening new avenues for applications in bio-medicine and, more generally, bio-nano-technology. The variety of RTILs offers a vast playground for future studies and potential applications.
Identifiers
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Registered trials
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