Evidence map›Paper›PMID 29754277›Full record

ArticleCalcified tissue international2018

Proton Pump Inhibitor Use, H

Julie M Paik, Harold N Rosen, Catherine M Gordon, Gary C Curhan

Abstract read
In one paragraph

Article in Calcified tissue international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Proton pump inhibitor use is associated with increased complications compared to H2-receptor antagonists following multi-level lumbar fusion: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Review
  3. Review
  4. Proton Pump Inhibitors and Bone Health: An Update Narrative Review.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Obstructive Sleep Apnea and Risk for Incident Vertebral and Hip Fracture in Women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julie M PaikChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. jmpaik@bwh.harvard.edu.
Harold N RosenEndocrinology Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Catherine M GordonDivision of Adolescent and Transition Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Gary C CurhanChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

Funding

Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Sex-related differences in incidence rates of nephrolithiasisK24DK091417 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI CURHAN, GARY C. · 2011 to 2020
$1.5M
Novel Risk Factors for Vertebral Fractures in Health and Chronic Kidney DiseaseK23DK100447 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI PAIK, JULIE · 2013 to 2017
$938k
NCI NIH HHS UM1 CA186107NIDDK NIH HHS K23 DK100447NIDDK NIH HHS K24 DK091417
6 · The paper itself

Abstract

The few prospective studies examining the relation between proton pump inhibitor (PPI) use and risk of vertebral fracture (VF) suggest a higher risk, but the magnitude of the association has been inconsistent. Moreover, no prospective studies have examined the association between substantially longer duration of PPI use and VF risk. Our objective was to determine the association between PPI use, H

Indexed as

AdultCohort StudiesFemaleHistamine H2 AntagonistsHumansIncidenceMiddle AgedProspective StudiesProton Pump InhibitorsRisk FactorsSpinal FracturesSurveys and QuestionnairesHistamine H2 AntagonistsProton Pump InhibitorsH2-receptor antagonistNurses’ health studyProspective studyProton pump inhibitorVertebral fracture

Identifiers

PMID29754277
PMCPMC6231994

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.