ArticleMikrochimica acta2018
Time-resolved determination of Fe(II) ions using cysteine-bridged Mn-doped ZnS quantum dots as a phosphorimetric probe.
Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 15 citations in OpenAlex.
- Development of Time-Resolved Luminescence Measurement Instruments for Biosensing and Bioimaging - An Overview.Measurement : journal of the International Measurement Confederation · 2025Article
- Review of Mn-Doped Semiconductor Nanocrystals for Time-Resolved Luminescence Biosensing/Imaging.ACS applied nano materials · 2022Article
- Synthesis of Poly-Amino Acid Ionic Liquid Up-Conversion Fluorescent Probe and its Application in Fe(II)/Fe(III) Speciation Analysis.Journal of fluorescence · 2020Article
- Toxicity and serum metabolomics investigation of Mn-doped ZnS quantum dots in mice.International journal of nanomedicine · 2019Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
A time-resolved phosphorescence (TRP) is applied to the highly sensitive determination of Fe(II) ions. The method is based on the use of a phosphorescent probe consisting of cysteine-bridged Mn-doped ZnS quantum dots (Mn/ZnS QDs). The presence of cysteine enhances the phosphorescence of the QDs and also increases the efficiency of quenching caused by Fe(II) ions. This results in strongly improved selectivity for Fe(II). The linear response is obtained in the concentration range of 50-1000 nM with a 19 nM detection limit. Phosphorescence is recorded at excitation/emission peaks of 301/602 nm. The interference of short-lived fluorescent and scattering background from the biological fluids is eliminated by using the TRP mode with a delay time of 200 μs. The determination of Fe(II) in human serum samples spiked at a 150 nM level gave a 92.4% recovery when using the TRP mode, but only 52.4% when using steady-state phosphorescence. This demonstrates that this probe along with TRP detection enables highly sensitive and accurate determination of Fe(II) in serum. Graphical abstract Schematic of a novel phosphorescent method for the detection of Fe
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