Evidence map›Paper›PMID 29754161›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Motion-corrected whole-heart PET-MR for the simultaneous visualisation of coronary artery integrity and myocardial viability: an initial clinical validation.

Camila Munoz, Karl P Kunze, Radhouene Neji, Teresa Vitadello, Christoph Rischpler, René M Botnar, Stephan G Nekolla, Claudia Prieto

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. PET/MR imaging of inflammation in atherosclerosis.Nature biomedical engineering · 2023
    Review
  4. Article
  5. Article
  6. Synergistic motion compensation strategies for positron emission tomography when acquired simultaneously with magnetic resonance imaging.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021
    Review
  7. Evaluation of synergistic image registration for motion-corrected coronary NaF-PET-MR.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021
    Article
  8. Data-driven, projection-based respiratory motion compensation of PET data for cardiac PET/CT and PET/MR imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Camila MunozSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor, Lambeth Wing, St Thomas' Hospital, London, SE1 7EH, UK. camila.munoz@kcl.ac.uk.ORCID 0000-0001-5278-4546
Karl P KunzeNuklearmedizinische Klinik und Poliklinik, Technische Universität München, Munich, Germany.
Radhouene NejiSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor, Lambeth Wing, St Thomas' Hospital, London, SE1 7EH, UK.
Teresa VitadelloNuklearmedizinische Klinik und Poliklinik, Technische Universität München, Munich, Germany.
Christoph RischplerNuklearmedizinische Klinik und Poliklinik, Technische Universität München, Munich, Germany.
René M BotnarSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor, Lambeth Wing, St Thomas' Hospital, London, SE1 7EH, UK.
Stephan G NekollaNuklearmedizinische Klinik und Poliklinik, Technische Universität München, Munich, Germany.
Claudia PrietoSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor, Lambeth Wing, St Thomas' Hospital, London, SE1 7EH, UK.
Klinik und Poliklinik für Nuklearmedizin · DESt Thomas' Hospital · GB

Funding

Deutsche Forschungsgemeinschaft 8810001759Engineering and Physical Sciences Research Council EP/L015226/1Engineering and Physical Sciences Research Council EP/N009258/1Medical Research Council MR/L009676/1Wellcome TrustWellcome Trust WT 203148/Z/16/Z
6 · The paper itself

Abstract

purposeCardiac PET-MR has shown potential for the comprehensive assessment of coronary heart disease. However, image degradation due to physiological motion remains a challenge that could hinder the adoption of this technology in clinical practice. The purpose of this study was to validate a recently proposed respiratory motion-corrected PET-MR framework for the simultaneous visualisation of myocardial viability (

methodsA cohort of 14 patients was scanned with the proposed PET-CMRA framework. PET and CMRA images were reconstructed with and without the proposed motion correction approach for comparison purposes. Metrics of image quality including visible vessel length and sharpness were obtained for CMRA for both the right and left anterior descending coronary arteries (RCA, LAD), and relative increase in

resultsMotion correction increased CMRA visible vessel length by 49.9% and 32.6% (RCA, LAD) and vessel sharpness by 12.3% and 18.9% (RCA, LAD) on average compared to uncorrected images. Coronary lumen delineation on motion-corrected CMRA images was in good agreement with X-ray angiography findings. For PET, motion correction resulted in an average 8% increase in

conclusionThe feasibility of the PET-CMRA framework for simultaneous cardiac PET-MR imaging in a short and predictable scan time (~11 min) has been demonstrated in 14 patients with CTO. Motion correction increased visible length and sharpness of the coronary arteries by CMRA, and improved delineation of the myocardium by

Indexed as

Magnetic Resonance ImagingMovementPositron-Emission TomographyTissue SurvivalAgedCoronary VesselsFemaleHeartHumansImage Processing, Computer-AssistedMaleMiddle AgedMyocardiumTime FactorsCardiac PET-MRCoronary artery diseaseCoronary MR angiographyMotion correction

Identifiers

PMID29754161
PMCPMC6132558
OpenAlexW2801341141

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.