Evidence map›Paper›PMID 29754030›Full record

ArticleDrug and alcohol dependence2018

Receipt of alcohol-related care among patients with HCV and unhealthy alcohol use.

Mandy D Owens, George N Ioannou, Judith L Tsui, E Jennifer Edelman, Preston A Greene, Emily C Williams

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mandy D OwensHealth Services Research and Development (HSRandD), Veterans Affairs (VA) Puget Sound Health Care System, Center of Innovation for Veteran-Centered Value-Driven Care (COIN), 1660 S. Columbian Way, Mailstop S-152, Seattle, WA, 98108, USA; Department of Health Services, University of Washington, 1959 NE Pacific St., Magnuson Health Sciences Center, Room H-680, Box 357660, Seattle, WA, 98195, USA. Electronic address: mandy.owens@va.gov.
George N IoannouDepartment of Medicine, University of Washington School of Medicine, RR-512, Health Sciences Building, Box 356420, 1959 NE Pacific Street, Seattle, WA, 98195, USA.
Judith L TsuiDepartment of Medicine, University of Washington School of Medicine, RR-512, Health Sciences Building, Box 356420, 1959 NE Pacific Street, Seattle, WA, 98195, USA.
E Jennifer EdelmanYale Schools of Medicine and Public Health, 333 Cedar St., New Haven, CT, 06510, USA.
Preston A GreeneHealth Services Research and Development (HSRandD), Veterans Affairs (VA) Puget Sound Health Care System, Center of Innovation for Veteran-Centered Value-Driven Care (COIN), 1660 S. Columbian Way, Mailstop S-152, Seattle, WA, 98108, USA.
Emily C WilliamsHealth Services Research and Development (HSRandD), Veterans Affairs (VA) Puget Sound Health Care System, Center of Innovation for Veteran-Centered Value-Driven Care (COIN), 1660 S. Columbian Way, Mailstop S-152, Seattle, WA, 98108, USA; Department of Health Services, University of Washington, 1959 NE Pacific St., Magnuson Health Sciences Center, Room H-680, Box 357660, Seattle, WA, 98195, USA.
University of Washington · USHealth Services Research & Development · US

Funding

Alcohol-related Care & Outcomes for Outpatients with HIV in a National VA CohortR21AA022866 · NIAAA · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI BRADLEY, KATHARINE ANTHONY, WILLIAMS, EMILY CATERINA · 2015 to 2016
$434k
NIAAA NIH HHS R21 AA022866
6 · The paper itself

Abstract

backgroundAlcohol use-particularly unhealthy alcohol use-exacerbates risks associated with Hepatitis C virus (HCV). However, whether unhealthy alcohol use is appropriately addressed among HCV+ patients is understudied. We examined receipt of alcohol-related care among HCV+ patients and unhealthy alcohol use.

methodsAll positive alcohol screens (AUDIT-C score ≥5) documented 10/01/09-5/30/13 were identified from national electronic health records data from the Veterans Health Administration (VA). Regression models estimated unadjusted and adjusted proportions of HCV+ and HCV- patients receiving 1) brief intervention within 14 days of positive screening, 2) specialty addictions treatment, and 3) pharmacotherapy for alcohol use disorder (AUD) in the year following positive screening. Adjusted models included demographics, alcohol use severity, and mental health and substance use disorder comorbidities.

resultsAmong 830,825 VA outpatients with positive alcohol screening, 31,841 were HCV+. Among HCV+, unadjusted and adjusted prevalences were 69.2% (CI, 68.7-69.6) and 71.9% (CI, 71.4-72.4) for brief intervention, 29.9% (CI, 29.4-30.4) and 12.7% (CI 12.5-12.9) for specialty addictions treatment, and 5.9% (CI, 5.7-6.1) and 3.3% (CI, 3.1-3.4) for pharmacotherapy, respectively. Among the 20,320 (64%) patients with HCV and documented AUD, unadjusted and adjusted prevalences were 40.0% (CI, 39.3-40.6) and 26.7% (CI, 26.3-27.1) for specialty addictions treatment and 8.1% (CI, 7.7-8.4) and 6.4% (CI, 6.1-6.6) for pharmacotherapy, respectively. Receipt of alcohol-related care was generally similar across HCV status.

conclusionsFindings highlight under-receipt of recommended alcohol-related care, particularly pharmacotherapy, among patients with HCV and unhealthy alcohol use who are particularly vulnerable to adverse influences of alcohol use.

Indexed as

VeteransAdolescentAdultAgedAlcoholismAmbulatory CareElectronic Health RecordsFemaleHepatitis CHumansMaleMiddle AgedUnited StatesUnited States Department of Veterans AffairsVeterans HealthYoung AdultAlcoholAlcohol use disordersBrief interventionHCV

Identifiers

PMID29754030
PMCPMC5999587
OpenAlexW2800693492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.