Evidence map›Paper›PMID 29753993›Full record

ArticleDevelopmental cognitive neuroscience2018

Reliability of neural activation and connectivity during implicit face emotion processing in youth.

Simone P Haller, Katharina Kircanski, Joel Stoddard, Lauren K White, Gang Chen, Banafsheh Sharif-Askary, Susan Zhang, Kenneth E Towbin, Daniel S Pine, Ellen Leibenluft and 1 more

Abstract read
In one paragraph

Article in Developmental cognitive neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
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  9. Attentional biases in human anxiety.Neuroscience and biobehavioral reviews · 2022
    Review
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  15. Common and specific dimensions of internalizing disorders are characterized by unique patterns of brain activity on a task of emotional cognitive control.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2020
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Simone P HallerEmotion and Development Branch, National Institute of Mental Health, USA. Electronic address: simone.haller@nih.gov.
Katharina KircanskiEmotion and Development Branch, National Institute of Mental Health, USA.
Joel StoddardDepartment of Psychiatry, University of Colorado School of Medicine, USA.
Lauren K WhiteChildren's Hospital of Philadelphia, Lifespan Brain Institute, USA.
Gang ChenScientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, USA.
Banafsheh Sharif-AskaryDuke University, School of Medicine, USA.
Susan ZhangEmotion and Development Branch, National Institute of Mental Health, USA.
Kenneth E TowbinEmotion and Development Branch, National Institute of Mental Health, USA.
Daniel S PineEmotion and Development Branch, National Institute of Mental Health, USA.
Ellen LeibenluftEmotion and Development Branch, National Institute of Mental Health, USA.
Melissa A BrotmanEmotion and Development Branch, National Institute of Mental Health, USA.

Funding

fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
The Pathophysiology and Treatment Of Children With Severe Mood DysregulationZIAMH002786 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2009 to 2023
$34.0M
Scientific and Statistical Computing CoreZICMH002888 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI TAYLOR, PAUL · 2009 to 2025
$30.9M
Fmri Studies Of Risk For Mood And Anxiety Disorders In ChildrenZIAMH002782 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$28.3M
Unit on Neuroscience and Novel TherapeuticsZIAMH002969 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BROTMAN, MELISSA · 2019 to 2025
$13.8M
The Phenomenology And Neurophysiology Of Juvenile Bipolar DisorderZIAMH002778 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2009 to 2017
$10.8M
The Phenomenology And Neurophysiology Of Juvenile Bipolar DisorderZ01MH002778 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2000 to 2008
$3.1M
The Characterization And Treatment Of Children With Severe Mood DysregulationZ01MH002786 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2002 to 2008
$2.8M
Fmri Studies Of Pediatric Mood And Anxiety DisordersZ01MH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2002 to 2008
$1.5M
Intramural NIH HHS Z01 MH002778Intramural NIH HHS Z01 MH002781Intramural NIH HHS Z01 MH002786Intramural NIH HHS ZIA MH002778Intramural NIH HHS ZIA MH002781Intramural NIH HHS ZIA MH002786
6 · The paper itself

Abstract

Face emotion imaging paradigms are widely used in both healthy and psychiatric populations. Here, in children and adolescents, we evaluate the test-retest reliability of blood oxygenation-level dependent (BOLD) activation and task-based functional connectivity on a widely used implicit face emotion processing task (i.e., gender labeling). Twenty-five healthy youth (M age = 13.97 year s; 60% female) completed two functional magnetic resonance imaging (fMRI) scan sessions approximately two months apart. Participants identified the gender of faces displaying angry, fearful, happy, and neutral emotions. A Bayesian adaptation of the intraclass correlation (ICC) assessed reliability of evoked BOLD activation and amygdala seed-based functional connectivity on task events vs. baseline as well as contrasts between face emotions. For each face emotion vs. baseline, good reliability of activation was demonstrated across key emotion processing regions including middle, medial, and inferior frontal gyri. However, contrasts between face emotions yielded variable results. Contrasts of angry to neutral or happy faces exhibited good reliability of amygdala connectivity to prefrontal regions. Contrasts of fearful to happy faces exhibited good reliability of activation in the anterior cingulate. Findings inform the reproducibility literature and emphasize the need for continued evaluation of task reliability.

Indexed as

EmotionsFacial ExpressionAdolescentAmygdalaAngerBayes TheoremChildFacial RecognitionFearFemaleGyrus CinguliHappinessHumansMagnetic Resonance ImagingMaleOxygenOxygenChildren and adolescentsEmotion processingfMRIReliability

Identifiers

PMID29753993
PMCPMC6054466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.