ArticleSleep medicine2019
NREM parasomnias: a treatment approach based upon a retrospective case series of 512 patients.
Article in Sleep medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Behavioral and psychological treatments for NREM parasomnias: A systematic review.Sleep medicine · 2023Pooled it
- Sexsomnia: an umbrella review of clinical, neurophysiological and diagnostic evidence.Frontiers in neurologyPooled it
- Self-Reported Precipitating and Priming Factors for Somnambulism in Adult Sleepwalkers.Journal of sleep research · 2026Article
- Melatonin Use in Pediatrics: A Clinical Review on Indications, Multisystem Effects, and Toxicity.Children (Basel, Switzerland) · 2024Review
- Diagnosis and Management of NREM Sleep Parasomnias in Children and Adults.Diagnostics (Basel, Switzerland) · 2023Review
- Group Cognitive Behavioural Therapy for Non-Rapid Eye Movement Parasomnias: Long-Term Outcomes and Impact of COVID-19 Lockdown.Brain sciences · 2023Article
- Non-REM parasomnias: a scoping review of dreams and dreamlike mentation.Croatian medical journal · 2022Article
- Parasomnias during trans-meridian and long-distance travel: Critical literature review and clinical practice recommendations.Journal of sleep research · 2022Review
- NREM Sleep Parasomnias Commencing in Childhood: Trauma and Atopy as Perpetuating Factors.Clocks & sleep · 2022Article
- What respiratory physicians should know about parasomnias.Breathe (Sheffield, England) · 2022Review
- Disorders of arousal in 4 older men: evidence from clinical practice.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Integrative behavioral treatment for NREM parasomnias: a case series.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- A Novel Group Cognitive Behavioral Therapy Approach to Adult Non-rapid Eye Movement Parasomnias.Frontiers in psychiatry · 2021Article
- NonREM Disorders of Arousal and Related Parasomnias: an Updated Review.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Review
- Cotard parasomnia: le délire de negation that occur during the sleep-wake dissociation?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Sleep Disturbances in Patients with Autoimmune Encephalitis.Current neurology and neuroscience reports · 2020Review
- Successful Treatment of Somnambulism With OROS-Methylphenidate.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Video polysomnographic findings in non-rapid eye movement parasomnia.Journal of sleep research · 2019Article
- Adult NREM Parasomnias: An Update.Clocks & sleep · 2019Review
- Sleepwalking and prolonged partial sleep paralysis in a case of obstructive sleep apnea.Sleep science (Sao Paulo, Brazil)Article
Corrections and comments
- Erratum issued
Authors and funding
15 authors at 1 institution in 1 country.
Funding
Abstract
backgroundNon-REM parasomnias are not uncommon conditions in the general population. Current treatment options are based on small case series and reports. In this study, we aimed to present the clinical experience from a large cohort of patients. PATIENTS: Five hundred and twelve patients with Non-REM parasomnia or parasomnia overlap disorder (POD), who had undergone a video polysomnography and were exposed to treatment, were retrospectively identified. Treatment outcome was assessed based on patients' reports, and treatment approach on a locally accepted hierarchy of interventions.
resultsForty percent of patients were diagnosed with sleepwalking, 23.8% with mixed-phenotype and 10% with POD. Ultimately, 97.2% reported adequate control of their symptoms. Moreover, 60.1% were treated with pharmacotherapy and 32.0% without, consistent across all phenotypes (p = 0.09). Benzodiazepines were the most common drugs prescribed (47.1%, p < 0.05). In the end, 37.7% of our patients were receiving a benzodiazepine as part of their successful treatment, 11.7% an antidepressant, 9.2% a z-drug, and 10.7% melatonin. Finally, 13.2%, 12.1%, and 5.8% of our patients reported good control of their symptoms with sleep hygiene, management of sleep-disordered breathing, and psychological interventions (cognitive behavioral therapy [CBT] or mindfulness-based stress reduction [MBSR]), as monotherapy, respectively.
conclusionThe treatment approach to effective treatment of the patients with Non-REM parasomnias or POD offering first sleep hygiene advice, next treatment of concurrent sleep disorders and management of other priming factors like stress and anxiety, and lastly pharmacotherapy for Non-REM parasomnia is supported by our results. Non pharmacological interventions were effective in one third of our patients, and CBT/MBSR and melatonin appeared promising new treatments.
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