ArticleNeuroImage2018
Response of the multiple-demand network during simple stimulus discriminations.
Article in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 33 citations in OpenAlex.
- Attentional selection drives information convergence within macaque lateral prefrontal cortex.PNAS nexus · 2026Article
- Representation of top-down versus bottom-up attention in the right dorsolateral prefrontal cortex and superior parietal lobule.Behavioral and brain functions : BBF · 2025Article
- Creative connections: the neural correlates of semantic relatedness are associated with creativity.Communications biology · 2024Article
- Context-dependent neural preparation for information relevance vs. probability.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Graph Theory Further Revealed Visual Spatial Working Memory Impairment in Patients with Inflammatory Bowel Disease.Journal of inflammation research · 2024Article
- Context-independent scaling of neural responses to task difficulty in the multiple-demand network.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Dynamic brain activity states of memory impairment in stroke patients with varying motor outcomes.Frontiers in aging neuroscience · 2023Article
- Abnormal functional connectivities patterns of multidomain cognitive impairments in pontine stroke patients.Human brain mapping · 2022Article
- Dissociated brain functional connectivity of fast versus slow frequencies underlying individual differences in fluid intelligence: a DTI and MEG study.Scientific reports · 2022Article
- Integrated Intelligence from Distributed Brain Activity.Trends in cognitive sciences · 2020Review
- A Domain-General Cognitive Core Defined in Multimodally Parcellated Human Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Composition is the Core Driver of the Language-selective Network.Neurobiology of language (Cambridge, Mass.) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The multiple-demand (MD) network is sensitive to many aspects of task difficulty, including such factors as rule complexity, memory load, attentional switching and inhibition. Many accounts link MD activity to top-down task control, raising the question of response when performance is limited by the quality of sensory input, and indeed, some prior results suggest little effect of sensory manipulations. Here we examined judgments of motion direction, manipulating difficulty by either motion coherence or salience of irrelevant dots. We manipulated each difficulty type across six levels, from very easy to very hard, and additionally manipulated whether difficulty level was blocked, and thus known in advance, or randomized. Despite the very large manipulations employed, difficulty had little effect on MD activity, especially for the coherence manipulation. Contrasting with these small or absent effects, we observed the usual increase of MD activity with increased rule complexity. We suggest that, for simple sensory discriminations, it may be impossible to compensate for reduced stimulus information by increased top-down control.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.