Evidence map›Paper›PMID 29752965›Full record

ReviewMechanisms of ageing and development2018

RECQ helicase disease and related progeroid syndromes: RECQ2018 meeting.

Junko Oshima, Hisaya Kato, Yoshiro Maezawa, Koutaro Yokote

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Mechanisms of ageing and development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. How Important Are Genes to Achieve Longevity?International journal of molecular sciences · 2022
    Review
  3. Human RecQ Helicases in DNA Double-Strand Break Repair.Frontiers in cell and developmental biology · 2021
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Junko OshimaDepartment of Clinical Cell Biology and Medicine, Chiba University, Graduate School of Medicine, Chiba, Japan; Department of Pathology, University of Washington, Seattle, WA, USA. Electronic address: picard@uw.edu.
Hisaya KatoDepartment of Clinical Cell Biology and Medicine, Chiba University, Graduate School of Medicine, Chiba, Japan.
Yoshiro MaezawaDepartment of Clinical Cell Biology and Medicine, Chiba University, Graduate School of Medicine, Chiba, Japan.
Koutaro YokoteDepartment of Clinical Cell Biology and Medicine, Chiba University, Graduate School of Medicine, Chiba, Japan.
Chiba University · JP

Funding

International Registry of Werner SyndromeR01CA210916 · NCI · UNIVERSITY OF WASHINGTON · PI JUNKO OSHIMA · 2016 to 2026
$3.8M
NCI NIH HHS R01 CA210916
6 · The paper itself

Abstract

Progeroid syndrome is a group of disorders characterized by the early onset of diseases that are associated with aging. Best known examples are Werner syndrome, which is adult onset and results from disease-causing DNA sequence variants in the RecQ helicase gene WRN, and Hutchison-Gilford progeria syndrome, which is childhood-onset and results from unique, recurrent disease-causing DNA sequence variants of the gene LMNA that encodes nuclear intermediate filaments. Related single gene RecQ disorders are Bloom syndrome and Rothmund-Thomson syndrome. The RecQ disorders Cockayne syndrome and xeroderma pigmentosum result from disease-causing DNA sequence variants in genes involved in the nucleotide excision repair pathway. RECQ2018: The International Meeting on RECQ Helicases and Related Diseases was held on February 16-18, 2018 in Chiba, Japan. The purpose of the meeting was to facilitate clinical and research collaborations for the goal of developing effective treatments for RECQ disorders and other progeroid syndromes.

Indexed as

Cockayne SyndromeDNA RepairDNA Repair-Deficiency DisordersWerner Syndrome HelicaseAnimalsCongresses as TopicHumansJapanWerner Syndrome HelicaseWRN protein, humanAgingGenomic instabilityProgeroid syndromeRECQ2018Werner syndrome

Identifiers

PMID29752965
PMCPMC6217841
OpenAlexW2802429501

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.