Evidence map›Paper›PMID 29752665›Full record

ArticleObesity surgery2018

Microcirculatory Improvement Induced by Laparoscopic Sleeve Gastrectomy Is Related to Insulin Sensitivity Retrieval.

Stefano Ministrini, Chiara Fattori, Maria Anastasia Ricci, Vanessa Bianconi, Rita Paltriccia, Marcello Boni, Maria Teresa Paganelli, Gaetano Vaudo, Graziana Lupattelli, Leonella Pasqualini

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Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Stefano MinistriniDepartment of Medicine, Università degli Studi di Perugia, Perugia, Italy. stefano.mns@gmail.com.ORCID 0000-0003-4358-6411
Chiara FattoriDepartment of Medicine, Università degli Studi di Perugia, Perugia, Italy.
Maria Anastasia RicciDepartment of Medicine, Università degli Studi di Perugia, Perugia, Italy.
Vanessa BianconiDepartment of Medicine, Università degli Studi di Perugia, Perugia, Italy.
Rita PaltricciaDepartment of Medicine, Università degli Studi di Perugia, Perugia, Italy.
Marcello BoniGeneral Surgery, ASL Umbria2, "S.Giovanni Battista" Hospital, Foligno, PG, Italy.
Maria Teresa PaganelliGeneral and Emergency Surgery, "S. Maria della Misericordia" Hospital, Perugia, Italy.
Gaetano VaudoDepartment of Medicine, Università degli Studi di Perugia, Perugia, Italy.
Graziana LupattelliDepartment of Medicine, Università degli Studi di Perugia, Perugia, Italy.
Leonella PasqualiniDepartment of Medicine, Università degli Studi di Perugia, Perugia, Italy.
University of Perugia · ITAzienda Ospedaliera di Perugia · ITAzienda Ospedaliero Universitaria San Giovanni Battista · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsMicrovascular dysfunction is a potential factor explaining the association of obesity, insulin resistance, and vascular damage in morbidly obese subjects. The purpose of the study was to evaluate possible determinants of microcirculatory improvement 1 year after laparoscopic sleeve gastrectomy (LSG) intervention.

methodsThirty-seven morbidly obese subjects eligible for bariatric surgery were included in the study. Post-occlusive reactive hyperemia (PORH) of the forearm skin was measured as area of hyperemia (AH) by laser-Doppler flowmetry before LSG and after a 1-year follow-up.

resultsAfter intervention, we observed a significant reduction in BMI, HOMA index, HbA1c, and a significant increase of AH in all patients after surgery; this variation was significant only in those patients having insulin resistance or prediabetes/diabetes. Although significant correlation between the increase of AH and the reduction of both BMI, HOMA index, and HbA1c was observed, BMI was the only independent predictor of AH variation after LSG at the linear regression analysis.

conclusionsOur study shows that LSG intervention is correlated with a significant improvement in the microvascular function of morbidly obese subjects; this improvement seems to be related to the baseline degree of insulin-resistance and to the retrieval of insulin-sensitivity post-intervention.

Indexed as

Bariatric SurgeryGastrectomyCohort StudiesHumansInsulin ResistanceMicrocirculationObesity, MorbidPostoperative PeriodInsulin resistanceLaparoscopic sleeve gastrectomyMetabolic surgeryMicrocirculationMorbid obesity

Identifiers

PMID29752665
OpenAlexW2800428447

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.