Evidence map›Paper›PMID 29752634›Full record

ArticleDrug safety - case reports2018

Bilateral Mastectomy as Radical Treatment of Gynecomastia Secondary to Antiretroviral Therapy in a Low-Income Setting: A Case Report.

Mario Antunes, Marcella Schiavone, Damiano Pizzol, Francesco Di Gennaro, Rossana Ludovico, Angela De Palma

Open access · hybridAbstract read
In one paragraph

Article in Drug safety - case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mario AntunesDepartment of Surgery, Central Hospital of Beira, Beira, Mozambique.
Marcella SchiavoneDepartment of Emergency and Organ Transplantation, Section of Thoracic Surgery, University of Bari "Aldo Moro", Bari, Italy.
Damiano PizzolOperational Research Unit, Doctors with Africa CUAMM, Rua Fernao Mendes Pinto 165, Ponta Gea, 1363, Beira, Mozambique. d.pizzol@cuamm.org.ORCID http://orcid.org/0000-0003-4122-0774
Francesco Di GennaroClinic of Infection Diseases, University of Bari "Aldo Moro", Bari, Italy.
Rossana LudovicoPlastic Surgery Consultant Emergency Department, Mater Dei Hospital, Bari, Italy.
Angela De PalmaDepartment of Emergency and Organ Transplantation, Section of Thoracic Surgery, University of Bari "Aldo Moro", Bari, Italy.
Doctors with Africa Cuamm · ITUniversity of Bari Aldo Moro · ITMaputo Central Hospital · MZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gynecomastia is a common finding in males, with an incidence that varies widely globally. In 10-25% of cases, it is caused by drugs. Its pathophysiologic mechanism includes exposure to exogenous estrogens and medications that cause hypogonadism, antiandrogenic effects and hyperprolactinemia. Gynecomastia is associated with exposure to antiretroviral therapy (ART), particularly efavirenz. Sometimes surgery may be required as treatment. We report a case of a 46-year-old man receiving ART presenting with a marked bilateral breast enlargement who underwent bilateral mastectomy as the only successful treatment in a low-income setting.

Identifiers

PMID29752634
PMCPMC5948190
OpenAlexW2805819088

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.