Evidence map›Paper›PMID 29752526›Full record

Observational studyClinical research in cardiology : official journal of the German Cardiac Society2018

Application of the Bogossian formula for evaluation of the QT interval in pacemaker patients with stimulated left bundle branch block.

K F Weipert, H Bogossian, P Conzen, G Frommeyer, C Gemein, I Helmig, R Chasan, L Eckardt, M Seyfarth, B Lemke and 4 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical research in cardiology : official journal of the German Cardiac Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. QTc evaluation in patients with bundle branch block.International journal of cardiology. Heart & vasculature · 2020
    Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

K F WeipertDepartment of Cardiology and Angiology, Medical Clinic I, University Clinic of Gießen, Gießen, Germany.
H BogossianDepartment of Cardiology and Angiology, Märkische Kliniken GmbH, Klinikum Lüdenscheid, Lüdenscheid, Germany.
P ConzenDepartment of Cardiology and Angiology, Medical Clinic I, University Clinic of Gießen, Gießen, Germany.
G FrommeyerDivision of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
C GemeinDepartment of Cardiology and Angiology, Medical Clinic I, University Clinic of Gießen, Gießen, Germany.
I HelmigDepartment of Cardiology and Angiology, Medical Clinic I, University Clinic of Gießen, Gießen, Germany.
R ChasanDepartment of Cardiology and Angiology, Medical Clinic I, University Clinic of Gießen, Gießen, Germany.
L EckardtDivision of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
M SeyfarthDepartment of Cardiology, University Witten/Herdecke, Witten, Germany.
B LemkeDepartment of Cardiology and Angiology, Märkische Kliniken GmbH, Klinikum Lüdenscheid, Lüdenscheid, Germany.
M ZarseDepartment of Cardiology and Angiology, Märkische Kliniken GmbH, Klinikum Lüdenscheid, Lüdenscheid, Germany.
C W HammDepartment of Cardiology and Angiology, Medical Clinic I, University Clinic of Gießen, Gießen, Germany.
J SchmittDepartment of Cardiology and Angiology, Medical Clinic I, University Clinic of Gießen, Gießen, Germany.
D ErkapicDepartment of Cardiology and Angiology, Medical Clinic I, University Clinic of Gießen, Gießen, Germany. damir.erkapic@diakonie-sw.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe presence of left bundle branch block (LBBB) represents a particular challenge in properly measuring the QT interval. Here we demonstrate the applicability of the "Bogossian formula" in pacemaker patients with LBBB due to apical or nonapical right ventricular (RV) pacing and preserved left ventricular function.

methodsA total of 163 patients with a cardiac one- or two-chamber pacemaker were included in this prospective, multicentre observational study. Twelve-lead ECG recordings were obtained during both intrinsic rhythm and RV pacing with induced LBBB. The QT interval measured during LBBB was corrected using the Bogossian formula to obtain the "modified QT" (QTm). The QTmc interval was calculated with the Bazett formula, and this was compared with the QTc interval during intrinsic rhythm.

resultsEighty-three patients (78 ± 9 years; male n = 83) with apical and eighty patients (71 ± 13 years; male n = 80) with non-apical RV pacing were included in this study. In the apical group the QTmc was determined to be 444 ± 39 ms in paced rhythm and the QTc interval 413 ± 36 ms in intrinsic rhythm. In the non-apical group these values were 430 ± 34 ms in paced and 416 ± 32 ms in intrinsic rhythm.

conclusionThe Bogossian formula is a reliable tool for QTc interval evaluation in pacemaker patients with LBBB due to apical or non-apical RV pacing. However, an overestimation of 30 ms should be included in the calculation.

Indexed as

ElectrocardiographyAgedBundle-Branch BlockCardiac Pacing, ArtificialDiagnosis, Computer-AssistedFemaleFollow-Up StudiesHeart VentriclesHumansMaleProspective StudiesReproducibility of ResultsVentricular Function, LeftJT intervalLeft bundle branch blockLong QTPacemakerQT formulaQT interval

Identifiers

PMID29752526

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.